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Microbiologyopen. 2017 Jun;6(3). doi: 10.1002/mbo3.427. Epub 2016 Nov 21.
2
Distinguishing between resistance, tolerance and persistence to antibiotic treatment.区分抗生素治疗的耐药性、耐受性和持久性。
Nat Rev Microbiol. 2016 Apr;14(5):320-30. doi: 10.1038/nrmicro.2016.34.
3
Contribution of stress responses to antibiotic tolerance in Pseudomonas aeruginosa biofilms.应激反应对铜绿假单胞菌生物被膜中抗生素耐受性的影响
Antimicrob Agents Chemother. 2015 Jul;59(7):3838-47. doi: 10.1128/AAC.00433-15. Epub 2015 Apr 13.
4
Sublethal concentrations of carbapenems alter cell morphology and genomic expression of Klebsiella pneumoniae biofilms.亚致死浓度的碳青霉烯类药物会改变肺炎克雷伯菌生物被膜的细胞形态和基因表达。
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5
HTSeq--a Python framework to work with high-throughput sequencing data.HTSeq——一个用于处理高通量测序数据的Python框架。
Bioinformatics. 2015 Jan 15;31(2):166-9. doi: 10.1093/bioinformatics/btu638. Epub 2014 Sep 25.
6
Reverting antibiotic tolerance of Pseudomonas aeruginosa PAO1 persister cells by (Z)-4-bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one.(Z)-4-溴-5-(溴亚甲基)-3-甲基-2(5H)-呋喃酮恢复铜绿假单胞菌 PAO1 持留细胞的抗生素耐药性。
PLoS One. 2012;7(9):e45778. doi: 10.1371/journal.pone.0045778. Epub 2012 Sep 20.
7
Differential expression analysis for sequence count data.差异表达分析序列计数数据。
Genome Biol. 2010;11(10):R106. doi: 10.1186/gb-2010-11-10-r106. Epub 2010 Oct 27.
8
Persister cells.持留细胞。
Annu Rev Microbiol. 2010;64:357-72. doi: 10.1146/annurev.micro.112408.134306.
9
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Genome Res. 2009 Sep;19(9):1630-8. doi: 10.1101/gr.094607.109. Epub 2009 Jul 1.
10
The Sequence Alignment/Map format and SAMtools.序列比对/映射格式和 SAMtools。
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抗生素处理的铜绿假单胞菌转录组序列

Transcriptome Sequence of Antibiotic-Treated Pseudomonas aeruginosa.

作者信息

Esani Saika, Chen Tsute, Leung Kai P, Van Laar Tricia A

机构信息

Department of Biology, College of Science and Mathematics, California State University-Fresno, Fresno, California, USA.

The Forsyth Institute, Cambridge, Massachusetts, USA.

出版信息

Microbiol Resour Announc. 2019 Mar 21;8(12):e01367-18. doi: 10.1128/MRA.01367-18.

DOI:10.1128/MRA.01367-18
PMID:30938705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6430322/
Abstract

is known to tolerate antibiotic therapy during infection. This prevents clearance of infection and negatively impacts patient outcomes. Here, we report the transcriptome sequence of antibiotic-treated and untreated cultures and the differential gene expression observed when treated cells are compared to untreated cells.

摘要

已知其在感染期间耐受抗生素治疗。这会阻止感染的清除,并对患者的治疗结果产生负面影响。在此,我们报告了经抗生素处理和未经处理的培养物的转录组序列,以及将处理过的细胞与未处理的细胞进行比较时观察到的差异基因表达。