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饮食控制高血压法对于改善高血压疾病女性妊娠结局的疗效。

The efficacy of the Dietary Approaches to Stop Hypertension diet with respect to improving pregnancy outcomes in women with hypertensive disorders.

机构信息

Department of Clinical Nutrition, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China.

Department of Gynaecology and Obstetrics, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China.

出版信息

J Hum Nutr Diet. 2019 Dec;32(6):713-718. doi: 10.1111/jhn.12654. Epub 2019 Apr 3.

Abstract

BACKGROUND

The DASH (Dietary Approaches to Stop Hypertension) diet serves as a dietary pattern for the prevention and control of hypertension. The present study aimed to investigate whether the DASH diet can improve the outcomes of pregnancy with gestational hypertension (GH) and chronic hypertension.

METHODS

The current randomised controlled clinical trial was performed in 85 pregnant women diagnosed with GH and chronic hypertension between July 2015 and December 2017. The women were categorised into a control group (41 cases) and a DASH group (44 cases). Participants were followed until delivery. The clinical outcomes of mothers included gestational weeks of birth, delivery mode, postpartum haemorrhage and GH, as well as the incidence of pre-eclampsia during the second and third trimesters. Newborn measurements were collected by evaluating prematurity, birth weight, body length and neonatal Apgar score.

RESULTS

The incidence of pre-eclampsia, prematurity and low birth weight in the DASH group was lower than that in the control group (P < 0.05). Significant differences were also observed in gestational age at delivery and the newborn body length between the two groups (P < 0.05). We failed to find a significant difference in changes of delivery mode, postpartum haemorrhage, postpartum GH, mean birth weight and Apgar score (P > 0.05) between the two diets.

CONCLUSIONS

A DASH diet might comprise a potential strategy for improving the clinical outcomes in pregnant women with GH and chronic hypertension. Future robust clinical trials are warranted to corroborate these findings.

摘要

背景

DASH(停止高血压的饮食方法)饮食可作为预防和控制高血压的饮食模式。本研究旨在探讨 DASH 饮食是否可以改善妊娠合并妊娠期高血压(GH)和慢性高血压的结局。

方法

本随机对照临床试验于 2015 年 7 月至 2017 年 12 月期间在 85 名被诊断为 GH 和慢性高血压的孕妇中进行。将这些女性分为对照组(41 例)和 DASH 组(44 例)。参与者一直随访至分娩。母亲的临床结局包括分娩周数、分娩方式、产后出血和 GH 以及第二和第三孕期子痫前期的发生率。通过评估早产儿、出生体重、体长和新生儿 Apgar 评分来收集新生儿测量值。

结果

DASH 组的子痫前期、早产和低出生体重发生率低于对照组(P<0.05)。两组之间的分娩时胎龄和新生儿体长也存在显著差异(P<0.05)。两组之间的分娩方式、产后出血、产后 GH、平均出生体重和 Apgar 评分的变化无显著差异(P>0.05)。

结论

DASH 饮食可能是改善 GH 和慢性高血压孕妇临床结局的一种潜在策略。需要未来的稳健临床试验来证实这些发现。

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