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1
Mitogenicity of Mycoplasma fermentans for human lymphocytes.发酵支原体对人淋巴细胞的促有丝分裂活性。
Infect Immun. 1978 Jul;21(1):48-54. doi: 10.1128/iai.21.1.48-54.1978.
2
In vitro detection of Mycoplasma fermentans binding to B-lymphocytes in fresh peripheral blood using flow cytometry.运用流式细胞术在体外检测发酵支原体与新鲜外周血中B淋巴细胞的结合情况。
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Induced mouse spleen B-cell proliferation and secretion of immunoglobulin by lipid-associated membrane proteins of Mycoplasma fermentans incognitus and Mycoplasma penetrans.发酵支原体隐匿株和穿透支原体的脂质相关膜蛋白诱导小鼠脾脏B细胞增殖及免疫球蛋白分泌
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4
Activation of human lymphocyte subpopulations by Mycoplasma pneumoniae.
Scand J Immunol. 1977;6(11):1145-50. doi: 10.1111/j.1365-3083.1977.tb00353.x.
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Detection of Mycoplasma genus and Mycoplasma fermentans by PCR in patients with Chronic Fatigue Syndrome.采用聚合酶链反应（PCR）检测慢性疲劳综合征患者的支原体属及发酵支原体。
FEMS Immunol Med Microbiol. 1998 Dec;22(4):355-65. doi: 10.1111/j.1574-695X.1998.tb01226.x.
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[Detection of Mycoplasma arthritidis and Mycoplasma fermentans antibodies in rheumatoid arthritis patients by an immunoenzyme method].[用免疫酶法检测类风湿关节炎患者中的关节炎支原体和发酵支原体抗体]
Zh Mikrobiol Epidemiol Immunobiol. 1985 Jun(6):48-52.
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Mitogenic activity of Mycoplasma pulmonis. I. Stimulation of rat B and T lymphocytes.肺支原体的促有丝分裂活性。I. 对大鼠B淋巴细胞和T淋巴细胞的刺激作用
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8
In vitro studies on the mitogenic activity of mycoplasmal species toward lymphocytes.支原体物种对淋巴细胞的促有丝分裂活性的体外研究。
Rev Infect Dis. 1982 May-Jun;4 Suppl:S205-9. doi: 10.1093/clinids/4.supplement_1.s205.
9
Activation of B lymphocytes by mycoplasma mitogen(s).支原体促细胞分裂素对B淋巴细胞的激活作用。
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Detection of mycoplasma contamination lymphoblastoid cell lines by monoclonal antibodies.用单克隆抗体检测淋巴母细胞系中的支原体污染
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引用本文的文献

1
Genotypic and phenotypic analysis of Mycoplasma fermentans strains isolated from different host tissues.从不同宿主组织分离的发酵支原体菌株的基因型和表型分析。
J Clin Microbiol. 1998 May;36(5):1371-7. doi: 10.1128/JCM.36.5.1371-1377.1998.
2
Induced mouse spleen B-cell proliferation and secretion of immunoglobulin by lipid-associated membrane proteins of Mycoplasma fermentans incognitus and Mycoplasma penetrans.发酵支原体隐匿株和穿透支原体的脂质相关膜蛋白诱导小鼠脾脏B细胞增殖及免疫球蛋白分泌
Infect Immun. 1994 Sep;62(9):3916-21. doi: 10.1128/iai.62.9.3916-3921.1994.
3
In vitro influence of Mycoplasma penetrans on activation of peripheral T lymphocytes from healthy donors or human immunodeficiency virus-infected individuals.穿透支原体对健康供体或人类免疫缺陷病毒感染个体外周血T淋巴细胞激活的体外影响。
Infect Immun. 1995 Nov;63(11):4277-83. doi: 10.1128/iai.63.11.4277-4283.1995.
4
Antigenic mimicry of mammalian intermediate filaments by mycoplasmas.支原体对哺乳动物中间丝的抗原模拟
Infect Immun. 1985 May;48(2):587-91. doi: 10.1128/iai.48.2.587-591.1985.

本文引用的文献

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MYCOPLASMA SPECIES OF MAN.人类支原体物种
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SEPARATION OF VIABLE LYMPHOCYTES FROM HUMAN BLOOD.从人血中分离活淋巴细胞
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Growth on artificial medium of an agent associated with atypical pneumonia and its identification as a PPLO.一种与非典型肺炎相关的病原体在人工培养基上的生长及其被鉴定为类胸膜肺炎微生物。
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Reversible inhibition of mitosis in lymphocyte cultures by non-viable Mycoplasma.非存活支原体对淋巴细胞培养物有丝分裂的可逆性抑制作用。
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Possible mechanism for Mycoplasma inhibition of lymphocyte transformation induced by phytohaemagglutinin.支原体抑制植物血凝素诱导的淋巴细胞转化的可能机制。
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6
Antibodies to brain and other tissues in cases of Mycoplasma pneumoniae infection.肺炎支原体感染病例中针对脑及其他组织的抗体。
Clin Exp Immunol. 1971 Feb;8(2):319-33.
7
Mycoplasmas and bacteria in synovial fluid from patients with arthritis.关节炎患者滑液中的支原体和细菌。
Ann Rheum Dis. 1973 Jul;32(4):319-25. doi: 10.1136/ard.32.4.319.
8
Selective triggering of B cell subpopulations by mitogens.丝裂原对B细胞亚群的选择性触发。
Eur J Immunol. 1974 Nov;4(11):771-6. doi: 10.1002/eji.1830041113.
9
Differentiation of B cells: sequential appearance of responsiveness to polyclonal activators.B细胞的分化：对多克隆激活剂反应性的顺序出现。
Scand J Immunol. 1974;3(4):413-21. doi: 10.1111/j.1365-3083.1974.tb01274.x.
10
In vitro response of human lymphocytes to Mycoplasma pneumoniae.人淋巴细胞对肺炎支原体的体外反应。
Infect Immun. 1972 Apr;5(4):552-8. doi: 10.1128/iai.5.4.552-558.1972.

发酵支原体对人淋巴细胞的促有丝分裂活性。

Mitogenicity of Mycoplasma fermentans for human lymphocytes.

作者信息

Nilsson E

出版信息

Infect Immun. 1978 Jul;21(1):48-54. doi: 10.1128/iai.21.1.48-54.1978.

DOI:10.1128/iai.21.1.48-54.1978
PMID:309436
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC421955/
Abstract

The in vitro stimulation response of human lymphocytes to Mycoplasma fermentans was examined. M. fermentans stimulated DNA synthesis in blood lymphocytes from all of 20 healthy subjects examined. Only one of these subjects had complement-fixing antibodies to M. fermentans. Lymphocytes from 21 of 22 adenoids and from 1 spleen were also stimulated to DNA synthesis by M. fermentans. The organism induced DNA synthesis in both B and T lymphocytes from adenoids and spleen and preferentially in T lymphocytes from blood. M. fermentans was shown to activate adenoid lymphocytes to non-amtogem-specific antibody secretion demonstrable by a hemolytic plaque assay. It is concluded that M. fermentans can have a mitogenic effect on both B and T lymphocytes.

摘要

检测了人淋巴细胞对发酵支原体的体外刺激反应。发酵支原体刺激了所检测的20名健康受试者血液淋巴细胞中的DNA合成。这些受试者中只有一人有针对发酵支原体的补体结合抗体。22个腺样体中的21个以及1个脾脏中的淋巴细胞也受到发酵支原体刺激而发生DNA合成。该微生物在腺样体和脾脏的B淋巴细胞和T淋巴细胞中均诱导DNA合成，且优先在血液的T淋巴细胞中诱导合成。发酵支原体可激活腺样体淋巴细胞分泌非抗原特异性抗体，这可通过溶血空斑试验证实。结论是，发酵支原体可对B淋巴细胞和T淋巴细胞产生促有丝分裂作用。