Dipartimento di Medicina e Chirurgia, Centro Universitario di Odontoiatria, Università di Parma, Parma, Italy.
Dipartimento di Medicina e Chirurgia, Statistica Medica, Università di Parma, Parma, Italy.
Oral Dis. 2019 Jul;25(5):1335-1343. doi: 10.1111/odi.13104. Epub 2019 Apr 24.
The role of dental plaque in gingival lesions caused by oral lichen planus has not been fully defined. The aim of this clinical trial was to evaluate the effects of oral healthcare motivation on clinical variables in patients with gingival oral lichen planus.
Oral lichen planus patients with symptomatic gingival lesions were randomized in control and intervention groups. The intervention group was instructed to effectively remove bacterial biofilm from dental surfaces, while controls did not receive any advice. The outcome variables were as follows: quality of life (OHIP-14), pain, plaque index and clinical severity of the disease (Escudier index). Outcome variables were assessed at 0, 4 and 20 weeks and analysed using an ANOVA model for factorial design.
Data from 60 patients were collected. Regression analysis showed a significant positive trend of OHIP-14, plaque index and Escudier index in the intervention group compared to controls (p < 0.05). Pain did not prove significantly different (p = 0.408).
Plaque control improved both OHIP-14 and gingival lesion clinical severity. Oral hygienists should be involved in the multidisciplinary management of patients affected by oral lichen planus with gingival lesions.
口腔扁平苔藓引起的牙龈病变中，牙菌斑的作用尚未完全明确。本临床试验旨在评估口腔保健动机对患有牙龈口腔扁平苔藓患者临床变量的影响。
将有症状的牙龈口腔扁平苔藓患者随机分为对照组和干预组。干预组被指导从牙齿表面有效清除细菌生物膜，而对照组则未接受任何建议。观察指标为生活质量（OHIP-14）、疼痛、菌斑指数和疾病的临床严重程度（Escudier 指数）。在 0、4 和 20 周时评估观察指标，并使用析因设计的方差分析模型进行分析。
共收集了 60 例患者的数据。回归分析显示，与对照组相比，干预组的 OHIP-14、菌斑指数和 Escudier 指数呈显著正相关（p<0.05）。疼痛无显著差异（p=0.408）。
菌斑控制改善了 OHIP-14 和牙龈病变的临床严重程度。口腔卫生员应参与多学科管理患有牙龈口腔扁平苔藓的患者。
