Yheulon Christopher G, Millard Anthony J, Balla Fadi M, Jonsson Arinbjorn, Constantin Tina V, Singh Arvinpal, Srinivasan Jahnavi, Stetler Jamil, Patel Ankit, Lin Edward, Davis S Scott
Am Surg. 2019 Mar 1;85(3):252-255.
Polycystic ovary syndrome (PCOS) is a common disease among the bariatric population. However, there are limited data regarding the impact of laparoscopic sleeve gastrectomy (SG) on these patients. The study was conducted at University Hospital, United States. The purpose of this study was to examine per cent excess body weight loss (%EWL) and diabetes control in patients who have PCOS compared with those without PCOS. A total of 550 female patients underwent SG between December 2011 and October 2016. Retrospective analysis was completed to include follow-up data at 1, 3, 6, and 12 months and yearly after that. Outcomes measured were %EWL and hemoglobin A1c (HgbA1c). The mean and median follow-up for the entire cohort was 21 and 15 months, respectively. Seventy-eight per cent of patients completed at least 12 months of follow-up for %EWL, although only 21 per cent had similar follow-up for HgbA1c. PCOS patients had similar age (36.3 36.2 years, = 0.90), preoperative BMI (47.2 47.2, = 0.99), preoperative HgbA1c (6% 5.8%, = 0.31), conversion rate to gastric bypass, and other associated comorbidities compared with non-PCOS comparisons. There was no difference in %EWL at 12-month (49.7% 53.1%, = 0.53) or 24-month (43% 49.8%, = 0.46) postoperative intervals. There was no difference in absolute change of HgbA1c at 12 months (-0.47% -0.67%, = 0.39). SG has equivalent short-term results in %EWL and reduction in HgbA1c for patients who have PCOS and those who do not.
多囊卵巢综合征（PCOS）是肥胖人群中的一种常见疾病。然而，关于腹腔镜袖状胃切除术（SG）对这些患者影响的数据有限。该研究在美国大学医院进行。本研究的目的是检查患有PCOS的患者与未患PCOS的患者相比，其超重体重减轻百分比（%EWL）和糖尿病控制情况。2011年12月至2016年10月期间，共有550名女性患者接受了SG手术。完成了回顾性分析，纳入了术后1、3、6和12个月以及之后每年的随访数据。测量的结果指标为%EWL和糖化血红蛋白（HgbA1c）。整个队列的平均随访时间和中位随访时间分别为21个月和15个月。78%的患者完成了至少12个月的%EWL随访，尽管只有21%的患者对HgbA1c进行了类似的随访。与非PCOS患者相比，PCOS患者的年龄（36.3±36.2岁，P = 0.90）、术前体重指数（47.2±47.2，P = 0.99）、术前HgbA1c（6%±5.8%，P = 0.31）、转为胃旁路手术的比例以及其他相关合并症相似。术后12个月（49.7%±53.1%，P = 0.53）或24个月（43%±49.8%，P = 0.46）时，%EWL没有差异。术后12个月时，HgbA1c的绝对变化也没有差异（-0.47%±-0.67%，P = 0.39）。对于患有PCOS和未患PCOS的患者，SG在%EWL和降低HgbA1c方面具有相似的短期效果。
