Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, MN 55905, USA.
Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, MN 55905, USA.
Clin Liver Dis. 2019 May;23(2):167-176. doi: 10.1016/j.cld.2018.12.001. Epub 2019 Mar 1.
Celiac disease is a multisystem disorder. Celiac hepatitis characterized by gluten-responsive mild elevation of transaminases is the more common liver manifestation of celiac disease. Celiac disease may also be associated or coexist with other chronic liver disorders. Shared genetic risk and increased intestinal permeability have been suggested to be the most relevant events in the pathogenesis of liver injury in celiac disease. The aim of this article is to review the full spectrum of liver disorders in patients with celiac disease.
乳糜泻是一种多系统疾病。乳糜泻肝炎的特征是麸质反应性转氨酶轻度升高,是乳糜泻更常见的肝脏表现。乳糜泻也可能与其他慢性肝脏疾病有关或并存。遗传易感性和增加的肠通透性被认为是乳糜泻患者肝损伤发病机制中最相关的事件。本文旨在综述乳糜泻患者的所有肝脏疾病谱。