Hassan Ali Shaziya, S P Somashekhar, N Arun Kumar
1Department of Surgical Oncology, Manipal Comprehensive Cancer Center, Manipal University, HAL Airport Road, Bengaluru, Karnataka 560017 India.
Department of Surgical Oncology, Manipal Comprehensive Cancer Center, HAL Airport Road, Bengaluru, Karnataka 560017 India.
Indian J Surg Oncol. 2019 Mar;10(1):72-76. doi: 10.1007/s13193-018-0818-7. Epub 2018 Oct 16.
Worldwide, breast conservation has become increasingly accepted as the surgical management of breast cancer in clinical practice. Cancer care in India is also evolving tremendously with many cancer treatment centres following evidence-based practice hence the rates of breast conservation are expected to increase. Here, we are reporting the rate of breast-conserving surgery (BCS) at our centre. A retrospective study of 401 patients who underwent breast cancer surgery at a tertiary care centre in South India from January 2015 to August 2017 were analysed to study the rate of BCS. All early breast cancers (EBC) were offered BCS. For large operable breast cancer (LOBC) and locally advanced breast cancer (LABC), neoadjuvant chemotherapy (NACT) followed by BCS was offered to these patients who wish to conserve their breast. The mean age was 45 years. A total of 163 patients underwent BCS. Yearly, BCS rates were 38.8% in 2015, 36.7% in 2016 and 46.5% in 2017. Majority had EBC 310 (77.3%) of which 62.7% of T1 lesions ( = 51) had BCS, and 45.7% of T2 lesions ( = 258) had BCS of which 5 patients had to undergo NACT to preserve their breast whereas 100% Tis patient ( = 1) had mastectomy. Fifty patients had LOBC and only 2 (4%) patients had upfront BCS whereas 9 of them had to undergo NACT (18%). cT4 lesions had NACT followed by BCS in 2 patients. The rates of BCS have been increasing in India over the past few years. The majority of the women presented with EBC which makes them suitable for BCS.
在全球范围内，保乳手术在临床实践中已越来越被广泛接受为乳腺癌的外科治疗方式。印度的癌症治疗也在飞速发展，许多癌症治疗中心都遵循循证医学实践，因此保乳率有望提高。在此，我们报告我们中心的保乳手术（BCS）率。对2015年1月至2017年8月在印度南部一家三级护理中心接受乳腺癌手术的401例患者进行回顾性研究，以分析BCS率。所有早期乳腺癌（EBC）患者均接受BCS。对于可手术的大乳腺癌（LOBC）和局部晚期乳腺癌（LABC），对希望保留乳房的患者先进行新辅助化疗（NACT），然后再进行BCS。平均年龄为45岁。共有163例患者接受了BCS。2015年的BCS率为38.8%，2016年为36.7%，2017年为46.5%。大多数患者为EBC，共310例（77.3%），其中T1期病变中有62.7%（=51例）接受了BCS，T2期病变中有45.7%（=258例）接受了BCS，其中5例患者必须接受NACT以保留乳房，而Tis期患者（=1例）全部接受了乳房切除术。50例患者为LOBC，只有2例（4%）患者直接接受了BCS，而其中9例患者必须接受NACT（18%）。2例cT4期病变患者先接受NACT，然后进行BCS。在过去几年中，印度的BCS率一直在上升。大多数女性表现为EBC，这使她们适合接受BCS。
