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本文引用的文献

1
Paradigm Shift From Halstedian Radical Mastectomy to Personalized Medicine.从霍尔斯特德根治性乳房切除术到个性化医疗的范式转变。
J Breast Health. 2017 Apr 1;13(2):50-53. doi: 10.5152/tjbh.2017.312017. eCollection 2017 Apr.
2
Prediction of pathological response to neoadjuvant chemotherapy in breast cancer patients by imaging.通过影像学预测乳腺癌患者对新辅助化疗的病理反应
J Surg Res. 2018 May;225:175-180. doi: 10.1016/j.jss.2017.12.002. Epub 2018 Feb 21.
3
Prediction of Treatment Response to Neoadjuvant Chemotherapy in Breast Cancer by Subtype Using Tumor-infiltrating Lymphocytes.利用肿瘤浸润淋巴细胞通过亚型预测乳腺癌新辅助化疗的治疗反应
Anticancer Res. 2018 Apr;38(4):2311-2321. doi: 10.21873/anticanres.12476.
4
Ultrasound-based prediction of pathologic response to neoadjuvant chemotherapy in breast cancer patients.基于超声的乳腺癌新辅助化疗病理反应预测。
Breast. 2018 Jun;39:19-23. doi: 10.1016/j.breast.2018.02.028. Epub 2018 Mar 7.
5
Is Mastectomy Oncologically Safer than Breast-Conserving Treatment in Early Breast Cancer?在早期乳腺癌中，乳房切除术在肿瘤学上比保乳治疗更安全吗？
Breast Care (Basel). 2017 Dec;12(6):385-390. doi: 10.1159/000485737. Epub 2017 Dec 12.
6
Addressing the paradox of increasing mastectomy rates in an era of de-escalation of therapy: Communication strategies.解决治疗降级时代乳腺癌切除术率上升的悖论：沟通策略。
Breast. 2018 Apr;38:136-143. doi: 10.1016/j.breast.2017.12.010. Epub 2018 Jan 8.
7
Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials.新辅助化疗与辅助化疗治疗早期乳腺癌的长期疗效：来自十个随机试验的个体患者数据的荟萃分析。
Lancet Oncol. 2018 Jan;19(1):27-39. doi: 10.1016/S1470-2045(17)30777-5. Epub 2017 Dec 11.
8
Oncological safety and cosmetic outcomes in oncoplastic breast conservation surgery, a review of the best level of evidence literature.肿瘤整形保乳手术的肿瘤学安全性和美容效果：最佳证据水平文献综述
Breast Cancer (Dove Med Press). 2017 Aug 4;9:521-530. doi: 10.2147/BCTT.S113742. eCollection 2017.
9
Oncoplastic breast conservation surgery is oncologically safe when compared to wide local excision and mastectomy.与广泛局部切除和乳房切除术相比，肿瘤整形保乳手术在肿瘤学上是安全的。
Breast. 2017 Apr;32:179-185. doi: 10.1016/j.breast.2017.02.006. Epub 2017 Feb 17.
10
Trends in mastectomy and reconstruction for breast cancer; a twelve year experience from a tertiary care center.乳腺癌乳房切除术及重建的趋势；来自一家三级护理中心的12年经验。
Am J Surg. 2016 Dec;212(6):1201-1210. doi: 10.1016/j.amjsurg.2016.08.020. Epub 2016 Sep 29.

乳腺癌局部治疗的范式转变：从乳房切除术到保乳手术。

Paradigm shift in the local treatment of breast cancer: mastectomy to breast conservation surgery.

作者信息

Murugappan Kowsi, Saboo Apoorva, Kuo Lu, Ung Owen

机构信息

Royal Brisbane Breast Surgery Unit, Department of General Surgery, RBWH, Brisbane, Australia.

University of Queensland, Brisbane, Australia.

出版信息

Gland Surg. 2018 Dec;7(6):506-519. doi: 10.21037/gs.2018.09.01.

DOI:10.21037/gs.2018.09.01
PMID:30687624
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6323252/
Abstract

There have been fundamental changes in the approach to breast cancer management over the last century but the primary objective of achieving oncological safety remains unchanged. This evolution is highlighted with a summary of the key evidences in support of the oncological safety of breast conserving surgery (BCS) in early breast cancer (EBC) management. We will also discuss the increasingly pivotal role that neoadjuvant chemotherapy (NACT) may play, in the local treatment of EBC and locally advanced breast cancer (LABC) and the long-term surgical and oncological outcomes.

摘要

在过去的一个世纪里，乳腺癌的治疗方法发生了根本性的变化，但实现肿瘤学安全性的首要目标始终未变。早期乳腺癌（EBC）治疗中支持保乳手术（BCS）肿瘤学安全性的关键证据总结突出了这一演变过程。我们还将讨论新辅助化疗（NACT）在EBC和局部晚期乳腺癌（LABC）的局部治疗中可能发挥的日益关键的作用，以及长期的手术和肿瘤学结果。