Song Ruiya, Pei Bin, Ran Peng, Song Xiuyu
The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350004, China. Email:
Zhengdao Judicial Authentication, Xiamen Blood Center, Xiamen, Fujian 361004, China.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2019 Apr 10;36(4):384-387. doi: 10.3760/cma.j.issn.1003-9406.2019.04.023.
To analyze genetic polymorphisms of 21 autosomal short tandem repeat (STR) loci from Quanzhou Han Chinese groups using a GlobalFiler kit, and to assess its value for forensic practice.
For 402 unrelated Han individuals, allelic frequencies of 21 autosomal STR loci were determined by using the GlobalFiler kit. Genetic parameters of the 21 STR loci were calculated.
No deviation from Hardy-Weinberg equilibrium was observed for the 21 loci. Most of the loci were highly polymorphic. Observed heterozygosity has ranged from 0.637 to 0.945, power of discrimination has ranged from 0.801 to 0.991, polymorphism information content has ranged from 0.570 to 0.940, power of exclusion was between 0.337 to 0.888, and match probability was between 0.009 to 0.199.
GlobalFiler kit has a high value for personal identification and paternity testing for Han Chinese from Quanzhou.
使用GlobalFiler试剂盒分析泉州汉族群体21个常染色体短串联重复序列（STR）基因座的遗传多态性，并评估其在法医学实践中的价值。
对402名无亲缘关系的汉族个体，采用GlobalFiler试剂盒测定21个常染色体STR基因座的等位基因频率，并计算这21个STR基因座的遗传参数。
21个基因座均未观察到偏离哈迪-温伯格平衡的情况。大多数基因座具有高度多态性。观察杂合度范围为0.637至0.945，鉴别力范围为0.801至0.991，多态信息含量范围为0.570至0.940，排除概率在0.337至0.888之间，匹配概率在0.009至0.199之间。
GlobalFiler试剂盒对泉州汉族个体识别和亲子鉴定具有较高价值。
