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[微柱高效液相色谱法测定血液中地西泮及其代谢物]

[Determination of diazepam and its metabolites in the blood by microcolumn high-performance liquid chromatography].

作者信息

Faĭbushevich A A, Kuramshin R K, Iushkevich A M, Kolesnikov S I

出版信息

Farmakol Toksikol. 1986 Sep-Oct;49(5):20-2.

PMID:3095138
Abstract

A rapid, sensitive and specific quantitative method of simultaneous determination of diazepam and its pharmacologically active metabolites in biological fluids by means of high-performance liquid chromatography on a liquid chromatograph "Milichrom" was used for pharmacokinetic studies in the "mother-placenta-fetus" system.

摘要

采用高效液相色谱法，在“Milichrom”液相色谱仪上，建立了一种快速、灵敏、特异的同时测定生物流体中地西泮及其药理活性代谢物的定量方法，用于“母-胎盘-胎儿”系统的药代动力学研究。

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