描绘细胞外 RNA 揭示了独特载体。
Mapping Extracellular RNA Sheds Lights on Distinct Carriers.
机构信息
Krefting Research Centre, Institute of Medicine at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
出版信息
Cell. 2019 Apr 4;177(2):228-230. doi: 10.1016/j.cell.2019.03.027.
Circulating extracellular RNA can participate in cell-to-cell communication and can be used as a marker of disease. Currently, biological and technical variability prevents the field from reaching its full potential. In this issue of Cell and the April 24 issue of Cell Systems, three studies by the Extracellular RNA Communication Consortium (ERCC) (Murillo et al., 2019; Srinivasan et al., 2019; Rozowsky et al., 2019) address several aspects contributing to this variability and provide knowledge and platforms for empowering future studies.
循环细胞外 RNA 可参与细胞间通讯，可作为疾病的标志物。目前，生物学和技术的变异性阻碍了该领域发挥其全部潜力。在本期《细胞》杂志和 4 月 24 日的《细胞系统》杂志上，细胞外 RNA 通讯联合会（ERCC）的三项研究（Murillo 等人，2019 年；Srinivasan 等人，2019 年；Rozowsky 等人，2019 年）解决了导致这种变异性的几个方面，并为未来的研究提供了知识和平台。
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