Department of Neurology, Virginia Commonwealth University, 1101 East Marshall Street, PO Box 980599, 6th Floor, Room 6-013, Richmond, VA 23298, USA.
Department of Neurology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA.
Neurol Clin. 2019 May;37(2):303-333. doi: 10.1016/j.ncl.2019.01.013. Epub 2019 Mar 18.
"The vasculitic neuropathies encompass a wide range of disorders characterized by ischemic injury to the vasa nervorum. Patients with vasculitic neuropathies develop progressive, painful sensory or sensorimotor deficits that are typically multifocal or asymmetric. Depending on the underlying etiology, the vasculitis may be confined to the peripheral nervous system; may be one manifestation of a primary systemic vasculitis; or one manifestation of a systemic vasculitis that is secondary to underlying connective tissue disease, drug exposure, viral infection, or paraneoplastic syndrome. This article reviews the classification, clinical presentation, diagnostic approach, etiologies, and treatment of the vasculitic neuropathies."
血管炎性神经病包括一大类疾病，其特征是神经滋养血管发生缺血性损伤。血管炎性神经病患者出现进行性、疼痛性感觉或感觉运动功能障碍，通常为多灶性或不对称性。根据潜在病因，血管炎可能局限于周围神经系统；也可能是原发性系统性血管炎的一种表现；或继发于潜在结缔组织病、药物暴露、病毒感染或副肿瘤综合征的系统性血管炎的一种表现。本文综述了血管炎性神经病的分类、临床表现、诊断方法、病因和治疗。
