Baima José Pedro Soares, Silva Beatriz Carneiro Gondim, Vieira Vanessa Lopes, Meireles Luiz Pedro, Arai Milton Hideaki, Lino Angelina Maria Martins
Universidade de São Paulo (USP), Hospital das Clínicas, Faculdade de Medicina, Departamento de Neurologia, São Paulo, SP, Brasil.
Universidade de São Paulo (USP), Hospital das Clínicas, Faculdade de Medicina, Departamento de Medicina Interna, São Paulo, SP, Brasil.
Autops Case Rep. 2024 Jun 14;14:e2024493. doi: 10.4322/acr.2024.493. eCollection 2024.
HIV infection is a chameleon, mimicking several diseases. Herein, we report a previously healthy 39-year-old woman who, over 2 months, developed arthritis, weight loss, and confluent multiple mononeuropathy. Extensive laboratory investigation showed positive serology for HIV, with a CD4 count of 100 cells, and necrotizing vasculitis on a nerve biopsy not associated with CMV co-infection, allowing the diagnosis of polyarteritis nodosa-like vasculitis in an HIV-infected patient. Apart from the infection, HIV-related autoimmunity can affect any organ and contribute to the complexity of the clinical presentation of HIV infection.
HIV感染是一种变色龙般的疾病，会模仿多种病症。在此，我们报告一名此前健康的39岁女性，在两个月内出现了关节炎、体重减轻和多发性单神经炎。广泛的实验室检查显示HIV血清学呈阳性，CD4细胞计数为100个，神经活检显示为坏死性血管炎，与巨细胞病毒合并感染无关，从而确诊该HIV感染患者患有结节性多动脉炎样血管炎。除感染外，HIV相关的自身免疫可影响任何器官，并导致HIV感染临床表现的复杂性。
