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[小关节软骨成像的更新:聚焦于高场强磁共振成像]

[Update cartilage imaging of the small joints : Focus on high-field MRI].

作者信息

Heiss R, Janka R, Uder M, Nagel A M, Trattnig S, Roemer F W

机构信息

Institute of Radiology, University Hospital Erlangen, Maximiliansplatz 3, 91054, Erlangen, Deutschland.

Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Deutschland.

出版信息

Radiologe. 2019 Aug;59(8):732-741. doi: 10.1007/s00117-019-0521-x.

Abstract

BACKGROUND

Cartilage imaging of small joints is increasingly of interest, as early detection of cartilage damage may be relevant regarding individualized surgical therapies and long-term outcomes.

PURPOSE

The aim of this review is to explain modern cartilage imaging of small joints with emphasis on MRI and to discuss the role of methods such as CT arthrography as well as compositional and high-field MRI.

MATERIALS AND METHODS

A PubMed literature search was performed for the years 2008-2018.

RESULTS

Clinically relevant cartilage imaging to detect chondral damage in small joints remains challenging. Conventional MRI at 3 T can still be considered as a reference for cartilage imaging in clinical routine. In terms of sensitivity, MR arthrography (MR-A) and computed tomography arthrography (CT-A) are superior to non-arthrographic MRI at 1.5 T in the detection of chondral damage. Advanced degenerative changes of the fingers and toes are usually sufficiently characterized by conventional radiography. MRI at field strengths of 3 T and ultrahigh-field imaging at 7 T can provide additional quantifiable, functional and metabolic information.

CONCLUSION

Standardized cartilage imaging plays an important role in clinical diagnostics in the ankle joint due to the availability of different and individualized therapeutic concepts. In contrast, cartilage imaging of other small joints as commonly performed in clinical studies has not yet become standard of care in daily clinical routine. Although individual study results are promising, additional studies with large patient collectives are needed to validate these techniques. With rapid development of new treatment concepts radiological diagnostics will play a more significant role in the diagnosis of cartilage lesions of small joints.

摘要

背景

小关节软骨成像越来越受到关注,因为早期发现软骨损伤可能与个体化手术治疗及长期疗效相关。

目的

本综述旨在解释小关节的现代软骨成像,重点是磁共振成像(MRI),并讨论诸如CT关节造影以及成分分析和高场强MRI等方法的作用。

材料与方法

对2008年至2018年期间的PubMed文献进行检索。

结果

检测小关节软骨损伤的临床相关软骨成像仍然具有挑战性。3T常规MRI仍可被视为临床常规软骨成像的参考标准。在检测软骨损伤方面,磁共振关节造影(MR-A)和计算机断层扫描关节造影(CT-A)在敏感性上优于1.5T非关节造影MRI。手指和脚趾的晚期退行性改变通常通过传统X线摄影就能得到充分表征。3T场强的MRI和7T超高场成像可提供额外的可量化、功能和代谢信息。

结论

由于存在不同的个体化治疗理念,标准化软骨成像在踝关节临床诊断中发挥着重要作用。相比之下,临床研究中常见的其他小关节软骨成像尚未成为日常临床常规的标准诊疗方法。尽管个别研究结果很有前景,但仍需要更多纳入大量患者群体的研究来验证这些技术。随着新治疗理念的快速发展,放射诊断在小关节软骨损伤的诊断中将发挥更重要的作用。

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