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安大略省脆弱老年人动员(MOVE ON)实施的效果能否在新环境中复制:一项中断时间序列设计。

Can the effects of the mobilization of vulnerable elders in Ontario (MOVE ON) implementation be replicated in new settings: an interrupted time series design.

机构信息

Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.

Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

出版信息

BMC Geriatr. 2019 Apr 5;19(1):99. doi: 10.1186/s12877-019-1124-0.

Abstract

BACKGROUND

Bed rest for older hospitalized patients places them at risk for hospital-acquired morbidity. We previously evaluated an early mobilization intervention and found it to be effective at improving mobilization rates and decreasing length of stay on internal medicine units. The aim of this study was to conduct a replication study evaluating the impact of the evidence-informed mobilization intervention on surgery, psychiatry, medicine, and cardiology inpatient units.

METHODS

A multi-component early mobilization intervention was tailored to the local context at seven hospitals in Ontario, Canada. The primary outcome was patient mobilization measured by conducting visual audits twice a week, three times a day. Secondary outcomes were hospital length of stay and discharge destination, which were obtained from hospital decision support data. The study population was patients aged 65 years and older who were admitted to surgery, psychiatry, medicine, and cardiology inpatient units between March and August 2014. Using an interrupted time series design, the intervention was evaluated over three time periods-pre-intervention, during, and post-intervention.

RESULTS

A total of 3098 patients [mean age 78.46 years (SD 8.38)] were included in the overall analysis. There was a significant increase in mobility immediately after the intervention period compared to pre-intervention with a slope change of 1.91 (95% confidence interval [CI] 0.74-3.08, P-value = 0.0014). A decreasing trend in median length of stay was observed in the majority of the participating sites. Overall, a median length of stay of 26.24 days (95% CI 23.67-28.80) was observed pre-intervention compared to 23.81 days (95% CI 20.13-27.49) during the intervention and 24.69 days (95% CI 22.43-26.95) post-intervention. The overall decrease in median length of stay was associated with the increase in mobility across the sites.

CONCLUSIONS

MOVE increased mobilization and these results were replicated across surgery, psychiatry, medicine, and cardiology inpatient units.

摘要

背景

对于老年住院患者来说,卧床休息会增加医院获得性疾病的风险。我们之前评估了一种早期活动干预措施,发现它可以有效提高活动率并缩短内科病房的住院时间。本研究的目的是进行一项复制研究,评估基于证据的活动干预措施对手术、精神科、内科和心内科住院患者的影响。

方法

在加拿大安大略省的七家医院,根据当地情况对多组分早期活动干预措施进行了调整。主要结果是通过每周两次、每天三次进行视觉审核来衡量患者的活动情况。次要结果是住院时间和出院去向,这些数据是从医院决策支持数据中获得的。研究人群为年龄在 65 岁及以上、在 2014 年 3 月至 8 月期间入住手术、精神科、内科和心内科住院病房的患者。采用中断时间序列设计,在干预前、干预中和干预后三个时间段评估干预。

结果

共有 3098 名患者(平均年龄 78.46 岁[8.38 标准差])纳入总体分析。与干预前相比,干预后即刻活动能力显著增加,斜率变化为 1.91(95%置信区间[CI] 0.74-3.08,P 值=0.0014)。大多数参与的地点都观察到住院时间中位数呈下降趋势。总体而言,干预前的中位数住院时间为 26.24 天(95%CI 23.67-28.80),干预期间为 23.81 天(95%CI 20.13-27.49),干预后为 24.69 天(95%CI 22.43-26.95)。各地点活动能力增加与中位住院时间的总体减少有关。

结论

MOVE 提高了活动能力,这些结果在手术、精神科、内科和心内科住院患者中得到了复制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9618/6451288/d8d44e33c643/12877_2019_1124_Fig1_HTML.jpg

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