• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

正在消退的大疱性类天疱疮皮损内的粟丘疹

Milia within resolving bullous pemphigoid lesions.

作者信息

Amin Sima, Fiore Connie T, Paek So Yeon

机构信息

Texas A&M College of Medicine, College StationTexas.

Division of Dermatology, Baylor University Medical CenterDallasTexas.

出版信息

Proc (Bayl Univ Med Cent). 2019 Jan 14;32(1):90-92. doi: 10.1080/08998280.2018.1528962. eCollection 2019 Jan.

DOI:10.1080/08998280.2018.1528962
PMID:30956594
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6442898/
Abstract

Bullous pemphigoid (BP) is a blistering dermatosis characterized by an autoimmune response to two hemidesmosomal proteins, BP180 and BP230. We describe a case of an 80-year-old man diagnosed with BP by clinical features, histopathology, and immunosorbent assay who developed milia within resolving BP lesions. Milia formation during recovery is common in cases of mucous membrane pemphigoid and epidermolysis bullosa acquisita but has rarely been reported in cases of BP.

摘要

大疱性类天疱疮(BP)是一种水疱性皮肤病,其特征是对两种半桥粒蛋白BP180和BP230产生自身免疫反应。我们描述了一例80岁男性患者,通过临床特征、组织病理学和免疫吸附试验诊断为BP,在BP皮损消退过程中出现了粟丘疹。在黏膜类天疱疮和获得性大疱性表皮松解症病例中,恢复过程中形成粟丘疹很常见,但在BP病例中鲜有报道。

相似文献

1
Milia within resolving bullous pemphigoid lesions.正在消退的大疱性类天疱疮皮损内的粟丘疹
Proc (Bayl Univ Med Cent). 2019 Jan 14;32(1):90-92. doi: 10.1080/08998280.2018.1528962. eCollection 2019 Jan.
2
Refractory bullous pemphigoid leaving numerous milia during recovery.难治性大疱性类天疱疮在恢复过程中留下大量粟丘疹。
J Dermatol. 2014 Nov;41(11):1003-5. doi: 10.1111/1346-8138.12650.
3
Bullous pemphigoid with prominent milium formation.伴有显著粟丘疹形成的大疱性类天疱疮。
Acta Dermatovenerol Croat. 2013;21(1):35-8.
4
Autoimmune Subepidermal Bullous Diseases of the Skin and Mucosae: Clinical Features, Diagnosis, and Management.自身免疫性表皮下大疱性皮肤病:临床特征、诊断与治疗。
Clin Rev Allergy Immunol. 2018 Feb;54(1):26-51. doi: 10.1007/s12016-017-8633-4.
5
[Epidermolysis bullosa acquisita with Brunsting-Perry type pemphigoid: Diagnostic and therapeutic difficulties].获得性大疱性表皮松解症合并布伦斯廷-佩里型类天疱疮:诊断和治疗难题
Ann Dermatol Venereol. 2020 Jun-Jul;147(6-7):439-445. doi: 10.1016/j.annder.2020.01.005. Epub 2020 Mar 31.
6
Granulocyte-derived elastase and gelatinase B are required for dermal-epidermal separation induced by autoantibodies from patients with epidermolysis bullosa acquisita and bullous pemphigoid.大疱性类天疱疮和获得性大疱性表皮松解症患者的自身抗体诱导真皮-表皮分离需要粒细胞衍生的弹性蛋白酶和明胶酶B。
J Pathol. 2004 Dec;204(5):519-27. doi: 10.1002/path.1674.
7
Epidermolysis Bullosa Acquisita-Current and Emerging Treatments.获得性大疱性表皮松解症——当前及新出现的治疗方法
J Clin Med. 2023 Feb 1;12(3):1139. doi: 10.3390/jcm12031139.
8
Multiple milia formation in blistering diseases.水疱性疾病中的多发性粟丘疹形成。
Int J Womens Dermatol. 2020 Apr 1;6(3):199-202. doi: 10.1016/j.ijwd.2020.03.045. eCollection 2020 Jun.
9
Case report: Bullous pemphigoid arising in a patient with scleroderma and multiple sclerosis.病例报告:硬皮病和多发性硬化症患者并发大疱性类天疱疮。
Front Med (Lausanne). 2022 Dec 8;9:1055045. doi: 10.3389/fmed.2022.1055045. eCollection 2022.
10
Epidermolysis bullosa acquisita and anti-p200 pemphigoid as major subepidermal autoimmune bullous diseases diagnosed by floor binding on indirect immunofluorescence microscopy using human salt-split skin.获得性大疱性表皮松解症和抗p200类天疱疮是主要的表皮下自身免疫性大疱病,通过使用人盐裂皮肤的间接免疫荧光显微镜检查中的基底膜带结合来诊断。
Indian J Dermatol Venereol Leprol. 2017 Sep-Oct;83(5):550-555. doi: 10.4103/ijdvl.IJDVL_678_16.

引用本文的文献

1
Milia En Plaque After Bullous Pemphigoid: An Unusual Sequela.大疱性类天疱疮后的斑块状粟丘疹:一种不寻常的后遗症。
Cureus. 2024 Nov 19;16(11):e73992. doi: 10.7759/cureus.73992. eCollection 2024 Nov.
2
Bullous pemphigoid and milia: prevalence and clinical laboratory findings in a Brazilian sample.大疱性类天疱疮和粟粒疹:巴西样本中的患病率和临床实验室发现。
An Bras Dermatol. 2022 Jul-Aug;97(4):435-442. doi: 10.1016/j.abd.2021.10.003. Epub 2022 May 27.
3
Multiple milia formation in blistering diseases.水疱性疾病中的多发性粟丘疹形成。
Int J Womens Dermatol. 2020 Apr 1;6(3):199-202. doi: 10.1016/j.ijwd.2020.03.045. eCollection 2020 Jun.

本文引用的文献

1
Effectiveness and Safety of Rituximab in Recalcitrant Pemphigoid Diseases.利妥昔单抗治疗难治性天疱疮疾病的疗效和安全性。
Front Immunol. 2018 Feb 19;9:248. doi: 10.3389/fimmu.2018.00248. eCollection 2018.
2
Bullous pemphigoid associated with milia, increased serum IgE, autoantibodies against desmogleins, and refractory treatment in a young patient.一名年轻患者出现与粟丘疹、血清IgE升高、抗桥粒芯糖蛋白自身抗体相关的大疱性类天疱疮及难治性治疗情况。
An Bras Dermatol. 2017;92(5 Suppl 1):34-36. doi: 10.1590/abd1806-4841.20176124.
3
Bullous Pemphigoid: A Review of its Diagnosis, Associations and Treatment.大疱性类天疱疮:诊断、相关因素及治疗综述
Am J Clin Dermatol. 2017 Aug;18(4):513-528. doi: 10.1007/s40257-017-0264-2.
4
A randomized double-blind trial of intravenous immunoglobulin for bullous pemphigoid.静脉注射免疫球蛋白治疗大疱性类天疱疮的随机双盲试验。
J Dermatol Sci. 2017 Feb;85(2):77-84. doi: 10.1016/j.jdermsci.2016.11.003. Epub 2016 Nov 9.
5
Treatment of recalcitrant bullous pemphigoid (BP) with a novel protocol: A retrospective study with a 6-year follow-up.采用新方案治疗难治性大疱性类天疱疮(BP):一项 6 年随访的回顾性研究。
J Am Acad Dermatol. 2016 Apr;74(4):700-8.e3. doi: 10.1016/j.jaad.2015.11.030. Epub 2016 Feb 3.
6
Refractory bullous pemphigoid leaving numerous milia during recovery.难治性大疱性类天疱疮在恢复过程中留下大量粟丘疹。
J Dermatol. 2014 Nov;41(11):1003-5. doi: 10.1111/1346-8138.12650.
7
Bullous pemphigoid with prominent milium formation.伴有显著粟丘疹形成的大疱性类天疱疮。
Acta Dermatovenerol Croat. 2013;21(1):35-8.
8
The association of HLA-DQ7 with bullous pemphigoid is restricted to men.
Br J Dermatol. 1998 Jun;138(6):1085-90. doi: 10.1046/j.1365-2133.1998.02350.x.
9
Post-bullous milia.
Australas J Dermatol. 1996 Aug;37(3):153-4. doi: 10.1111/j.1440-0960.1996.tb01037.x.
10
Immunoelectron microscopy in subepidermal autoimmune bullous diseases: a prospective study of IgG and C3 bound in vivo in 32 patients.
J Invest Dermatol. 1987 Dec;89(6):567-73. doi: 10.1111/1523-1747.ep12461226.