在2-氯乙基膦酸存在下某些抗生素的生物合成。

Biogenesis of some antibiotics in the presence of 2-chloroethylphosphonic acid.

作者信息

Sharma A, Padwal-Desai S R

出版信息

Appl Environ Microbiol. 1986 Oct;52(4):605-6. doi: 10.1128/aem.52.4.605-606.1986.

DOI:10.1128/aem.52.4.605-606.1986

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC239083/

Abstract

2-Chloroethylphosphonic acid (CEPA) affected both the growth of and antibiotic production in Streptomyces aureofaciens, S. griseus, S. antibioticus, and Penicillium citrinum. Streptomyces strains seemed to be more sensitive to the presence of CEPA in the medium than did the fungus. A decrease in both growth and antibiotic production was observed with a concomitant increase in the concentration of the ethylene-releasing compound in the medium. Higher concentrations of CEPA completely inhibited the growth of the above microorganisms.

摘要

2-氯乙基膦酸（CEPA）影响了金色链霉菌、灰色链霉菌、抗生链霉菌和桔青霉的生长及抗生素产生。链霉菌菌株似乎比真菌对培养基中CEPA的存在更敏感。随着培养基中乙烯释放化合物浓度的增加，生长和抗生素产生均下降。较高浓度的CEPA完全抑制了上述微生物的生长。

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