Veyrat C, Gourtchiglouian C, Bas S, Abitbol G, Gramage J Y, Kalmanson D
Arch Mal Coeur Vaiss. 1986 Jul;79(8):1195-204.
The authors studied a group of 120 patients and a total of 137 valvular prostheses by ultrasonic pulsed Doppler (3 MHz). Fifty three of these prostheses were also investigated with continuous wave Doppler. Clinical, phonocardiographic and echocardiographic examination revealed 99 normal and 38 abnormal prostheses, the latter group comprising 42 dysfunctions (9 obstructions and 33 regurgitations), all confirmed by invasive studies. The lesions were graded into 3 degrees of severity. The methods used were the recording of velocity signals and two- and three-dimensional mapping in the pulsed Doppler mode, and the calculation of the haemodynamic parameters derived from measurements of blood velocity in the continuous wave mode. Pulsed Doppler correctly diagnosed 92 out of the 99 normal prostheses. The maximum systolic pressure gradient in aortic valve prostheses was 16 +/- 6 mmHg; the average early diastolic pressure gradient of the mitral valve prostheses was 10.01 +/- 3.34 mmHg, with a mean diastolic gradient of 4.52 +/- 0.71 mmHg and a mean pressure half time of 0.09 +/- 0.02 sec giving an average valve surface area of 2.45 +/- 0.57 cm2. The sensitivity and specificity of the diagnosis of valve dysfunction were 95 and 92 per cent respectively with a satisfactory evaluation of the degree of severity in 88 per cent of cases. In the 3 mitral valve prostheses with obstruction, significant abnormalities of pressure half time and value surface area were detected.(ABSTRACT TRUNCATED AT 250 WORDS)
作者通过超声脉冲多普勒(3兆赫)研究了一组120例患者及总共137个瓣膜假体。其中53个假体还采用连续波多普勒进行了研究。临床、心音图和超声心动图检查发现99个假体正常,38个异常,后一组包括42个功能障碍(9个狭窄和33个反流),所有这些均经侵入性研究证实。病变分为3级严重程度。所采用的方法包括在脉冲多普勒模式下记录速度信号以及进行二维和三维绘图,以及在连续波模式下根据血流速度测量值计算血流动力学参数。脉冲多普勒正确诊断出99个正常假体中的92个。主动脉瓣假体的最大收缩压梯度为16±6毫米汞柱;二尖瓣假体的平均舒张早期压力梯度为10.01±3.34毫米汞柱,平均舒张期梯度为4.52±0.71毫米汞柱,平均压力减半时间为0.09±0.02秒,平均瓣膜表面积为2.45±0.57平方厘米。瓣膜功能障碍诊断的敏感性和特异性分别为95%和92%,88%的病例对严重程度的评估令人满意。在3个有狭窄的二尖瓣假体中,检测到压力减半时间和瓣膜表面积有明显异常。(摘要截短于250字)