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二尖瓣位人工瓣膜的连续波多普勒评估:圣犹达医疗机械瓣膜与猪异种移植瓣膜的比较

[Continuous wave Doppler assessment of prosthetic valves in the mitral position: comparison of the St. Jude medical mechanical valve and the porcine xenograft valve].

作者信息

Kisanuki A, Tei C, Arikawa K, Natsugoe K, Otsuji Y, Kawazoe Y, Tanaka H, Morishita Y, Maruko M, Taira A

出版信息

J Cardiogr. 1985 Dec;15(4):1119-27.

PMID:3841894
Abstract

To assess the opening function of prosthetic valves in the mitral position with special reference to the type and size of the valve and the years since replacement, we recorded maximum flow velocity through the mitral orifice using continuous wave Doppler echocardiography for 50 patients with mitral valve replacement and 15 normal subjects. There were 33 patients with St. Jude Medical valves and 17 with porcine xenograft valves. An ultrasonic transducer was placed over the left ventricular apex and the direction of the ultrasonic beam was positioned to be parallel with mitral flow using the Doppler audio signals. A pressure gradient was calculated from continuous wave Doppler flow velocity with a simplified Bernoulli's equation proposed by Hatle et al. The peak and mean maximum flow velocity, mean pressure gradient across the valve and the pressure half time were measured to evaluate the opening function of the prosthetic valve. The results were as follows: All four measurements were significantly larger in patients with valve replacements than in normal subjects, and were significantly increased in patients with porcine xenograft valves compared to those with St. Jude Medical valves. The opening function was well maintained in patients having larger valves than in those having smaller ones in the group of St. Jude Medical valve replacement. In patients who had porcine xenograft valve for four years or more, the opening function was decreased the more years they had been implanted. We conclude that continuous wave Doppler echocardiography is a useful noninvasive method for the quantitative assessment of the diastolic opening function of the prosthetic mitral valve.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

为评估二尖瓣位人工瓣膜的开放功能,特别参考瓣膜类型、大小及置换后的年限,我们使用连续波多普勒超声心动图记录了50例二尖瓣置换患者及15名正常受试者通过二尖瓣口的最大流速。其中33例患者使用圣犹达医疗公司生产的瓣膜,17例使用猪异种移植瓣膜。将超声换能器置于左心室心尖上方,利用多普勒音频信号将超声束方向定位为与二尖瓣血流平行。根据哈特尔等人提出的简化伯努利方程,由连续波多普勒流速计算压力阶差。测量峰值和平均最大流速、瓣膜两端的平均压力阶差及压力减半时间,以评估人工瓣膜的开放功能。结果如下:所有四项测量值在瓣膜置换患者中均显著高于正常受试者,且与使用圣犹达医疗公司瓣膜的患者相比,使用猪异种移植瓣膜的患者各项测量值显著升高。在圣犹达医疗公司瓣膜置换组中,瓣膜较大的患者其开放功能维持得比瓣膜较小的患者更好。对于使用猪异种移植瓣膜达四年或更长时间的患者,瓣膜植入时间越长,开放功能下降越明显。我们得出结论,连续波多普勒超声心动图是定量评估人工二尖瓣舒张期开放功能的一种有用的非侵入性方法。(摘要截选至250词)

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