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采用聚乙烯醇修饰的氧化石墨烯制备导电的人源生物纳米电极。

Fabrication of conductive human bio-nanoelectrode from graphene oxide modified with polyvinyl alcohol.

机构信息

Department of Chemical Engineering, Faculty of Engineering, Minia University, El-Minya, Egypt.

Department of Biomedical Engineering, Faculty of Engineering, Minia, University, El-Minya, Egypt.

出版信息

IET Nanobiotechnol. 2019 Feb;13(1):1-5. doi: 10.1049/iet-nbt.2018.5125.

Abstract

It is time for electrodes prepared from graphene oxide (GO) to replace the traditional electrodes. However, GO is an electrically insulating material. However, in this study, a conductive electrode was prepared from GO modification with glycerol (GL) under the esterification reaction at 90°C for 3 h with sulphuric acid as a catalyst under vacuum conditions. Polyvinyl alcohol (PVA) acts as a polymer host. It was mixed with GO and modification was carried out under heating conditions. The mixture of the GO/GL/PVA nanocomposite was rapidly cooled and poured into the electrode mould. Finally, it is placed in a desiccator at room temperature for two days. The characterisation (Fourier transform infrared spectroscopy, X-ray diffraction, and scanning electron microscopy) proved that the ester bond was formed and a complete distribution of GO/GL into the matrix of PVA was verified. The GO/GL/PVA nanocomposite was tested for electrocardiogram (ECG) electrodes. The biopic instrument was used to compare the behaviour of the GO/GL/PVA plastic electrode and the commercial one. The results indicated that the GO/GL/PVA plastic electrode efficiently detected ECG signals after two months with high conductivity and lower noise than the commercial electrode. The GO/GL/PVA plastic electrode has been reported for the first time in the literature.

摘要

是时候用氧化石墨烯(GO)制备的电极来取代传统电极了。然而,GO 是一种电绝缘材料。然而,在这项研究中,通过在 90°C 下用硫酸作为催化剂在真空条件下进行酯化反应 3 小时,用甘油(GL)对 GO 进行改性,制备了一种导电电极。聚乙烯醇(PVA)作为聚合物主体。将其与 GO 混合,并在加热条件下进行改性。GO/GL/PVA 纳米复合材料的混合物被迅速冷却并倒入电极模具中。最后,将其放置在室温下的干燥器中两天。通过傅里叶变换红外光谱、X 射线衍射和扫描电子显微镜对其进行了表征,证明了酯键的形成,并且证实了 GO/GL 完全分布在 PVA 基质中。对 GO/GL/PVA 纳米复合材料进行了心电图(ECG)电极测试。使用生物电仪器比较了 GO/GL/PVA 塑料电极和商用电极的性能。结果表明,GO/GL/PVA 塑料电极在两个月后能够高效地检测 ECG 信号,具有较高的导电性和比商用电极更低的噪声。GO/GL/PVA 塑料电极在文献中首次被报道。

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