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钬激光保留射精功能的膀胱颈切开术治疗有排尿症状的小前列腺患者:短期功能结果

Ejaculation Sparing Bladder Neck Incision with Holmium Laser in Patients with Urinary Symptoms and Small Prostates: Short-Term Functional Results.

作者信息

Porreca Angelo, Mineo Bianchi Federico, D'Agostino Daniele, Sadini Paolo, Romagnoli Daniele, Del Rosso Alessandro, Cindolo Luca, Corsi Paolo, Schiavina Riccardo, Brunocilla Eugenio, Giampaoli Marco

机构信息

Department of Robotic Urological Surgery, Abano Terme Hospital, Abano Terme, Italy.

Department of Urology, University of Bologna, Bologna, Italy.

出版信息

Urol Int. 2019;103(1):102-107. doi: 10.1159/000499410. Epub 2019 Apr 9.

Abstract

BACKGROUND

The treatment options for male lower urinary tract symptoms (LUTS) widely range from self-monitoring to oral medications to surgical procedures. As far as concerns surgical treatment of obstructive LUTS, transurethral incision of the prostate is considered as the gold standard in patients with mild benign prostatic enlargement.

OBJECTIVES

The aim of our study is to describe this novel approach to perform ejaculation sparing Holmium laser bladder neck incision (ES-HoBNI), with particular regard to its effect on ejaculation and LUTS relief.

METHODS

We evaluated prospective clinical data from 143 consecutive patients who underwent ES-HoBNI at our institution from January 2012 to February 2018. Procedures were performed with a continuous flow 26 Ch resectoscope and a 550 µm holmium laser end-fire fiber. The stenotic bladder neck was deeply incised at 3 and 9'o clock down to the prostatic capsule in a retrograde direction to either side in front of the veromontanum.

RESULTS

Median Qmax, postvoid residual volume, International Prostate Symptom Score, and quality of life were 9 mL/s (7.4-10.2), 130 mL (100-190), 15 (13-19), and 3 (2-4), respectively. In total, 110 (76.9) reported regular anterograde ejaculation. Median operative time was 20 min (15-26). Median catheterization time and hospital stay were 3 days (3-4) and 22 h (20-24), respectively. Moreover, we have compared the frequency of anterograde ejaculation, which slightly increases after ES-HoBNI (77 vs. 81.2%) when compared to baseline data, despite not reaching statistical significancy.

CONCLUSIONS

ES-HoBNI is a safe, reproducible technique to relieve obstructive LUTS in men with small prostates while preserving ejaculation in younger and sexually active individuals.

摘要

背景

男性下尿路症状(LUTS)的治疗选择范围广泛,从自我监测到口服药物再到外科手术。就梗阻性LUTS的外科治疗而言,经尿道前列腺切开术被认为是轻度良性前列腺增生患者的金标准。

目的

我们研究的目的是描述这种保留射精功能的钬激光膀胱颈切开术(ES-HoBNI)的新方法,特别是其对射精和LUTS缓解的影响。

方法

我们评估了2012年1月至2018年2月在我院连续接受ES-HoBNI手术的143例患者的前瞻性临床数据。手术使用连续冲洗26 Ch电切镜和550 µm钬激光端射光纤进行。在前列腺小囊前方,于3点和9点位置向两侧逆行深切狭窄的膀胱颈直至前列腺包膜。

结果

最大尿流率(Qmax)、残余尿量、国际前列腺症状评分和生活质量的中位数分别为9 mL/s(7.4-10.2)、130 mL(100-190)、15(13-19)和3(2-4)。共有110例(76.9%)报告有规律的顺行射精。中位手术时间为20分钟(15-26)。中位导尿时间和住院时间分别为3天(3-4)和22小时(20-24)。此外,我们比较了顺行射精的频率,与基线数据相比,ES-HoBNI术后略有增加(77%对81.2%),尽管未达到统计学显著性。

结论

ES-HoBNI是一种安全、可重复的技术,可缓解前列腺较小男性的梗阻性LUTS,同时保留年轻和性活跃个体的射精功能。

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