Stasiak-Różańska Lidia, Płoska Justyna
Department of Biotechnology, Microbiology and Food Evaluation, Faculty of Food Sciences, Warsaw University of Life Sciences-SGGW, Nowoursynowska St. 166, 02-787 Warsaw, Poland.
Faculty of Horticulture, Biotechnology and Landscape Architecture, Warsaw University of Life Sciences-SGGW, Nowoursynowska St. 166, 02-787 Warsaw, Poland.
Polymers (Basel). 2018 Apr 14;10(4):438. doi: 10.3390/polym10040438.
Can microbial cellulose (MC) be used as a bio-carrier for 1,3-dihydroxy-2-propanone (DHA)? The aim of this study was to examine the possibility of using MC as a biomaterial for DHA transferring into the stratum corneum and inducing changes in skin color. The MC patches were obtained from strain and incubated in solutions with various concentrations of DHA (g·L: 20; 50; 80; 110) at 22 °C for 24 h. Afterwards; the patches were applied onto the skin for 15, 30, or 60 min. Skin color changes were assessed visually compared to a control patches without DHA. The intensity of skin color was increasing with the increase of DHA concentration and time of patches application. Application of MC patches with DHA (50 g·L) for 30 min ensured the color which was considered the closest to the desired natural tan effect. MC patches containing DHA can be biocarriers enabling DHA transport into the stratum corneum and causing skin color changes. Study results indicate a new possibility for industrial applications of MC; e.g., as a biocarrier in masking the symptoms of vitiligo or production of self-tanning agents in the form of masks.
微生物纤维素（MC）能否用作1,3 - 二羟基 - 2 - 丙酮（DHA）的生物载体？本研究的目的是探讨使用MC作为生物材料将DHA转移至角质层并引起皮肤颜色变化的可能性。MC贴片取自菌株，并在22°C下于不同浓度（g·L：20；50；80；110）的DHA溶液中孵育24小时。之后，将贴片贴于皮肤上15、30或60分钟。与不含DHA的对照贴片相比，通过肉眼评估皮肤颜色变化。皮肤颜色的强度随着DHA浓度和贴片应用时间的增加而增加。使用含50 g·L DHA的MC贴片30分钟可确保获得被认为最接近所需自然晒黑效果的颜色。含有DHA的MC贴片可以作为生物载体，使DHA转运至角质层并引起皮肤颜色变化。研究结果表明MC在工业应用方面有新的可能性，例如作为掩盖白癜风症状的生物载体或以面膜形式生产自晒黑剂。
