Post Graduate and Research Department of Chemistry, Bishop Moore College, Mavelikara, India.
Rajiv Gandhi Center for Biotechnology, Thiruvananthapuram, India.
Bioengineered. 2021 Dec;12(2):11463-11483. doi: 10.1080/21655979.2021.2009753.
Bacterial nanocellulose (BNC) has been emerging as a biomaterial of considerable significance in a number of industrial sectors because of its remarkable physico-chemical and biological characteristics. High capital expenses, manufacturing costs, and a paucity of some well-scalable methods, all of which lead to low BNC output in commercial scale, are major barriers that must be addressed. Advances in production methods, including bioreactor technologies, static intermittent, and semi-continuous fed batch technologies, and innovative outlay substrates, may be able to overcome the challenges to BNC production at the industrial scale. The novelty of this review is that it highlights genetic modification possibilities in BNC production to overcome existing impediments and open up viable routes for large-scale production, suitable for real-world applications. This review focuses on various production routes of BNC, its properties, and applications, especially the major advancement in food, personal care, biomedical and electronic industries.
细菌纳米纤维素（BNC）由于其显著的物理化学和生物学特性，已经成为许多工业领域中一种非常重要的生物材料。高资本支出、制造成本以及一些缺乏良好可扩展性方法，这些都导致 BNC 在商业规模上的产量较低，是必须解决的主要障碍。生产方法的进步，包括生物反应器技术、静态间歇和半连续流加批处理技术以及创新的衬底，可能能够克服工业规模上 BNC 生产的挑战。本综述的新颖之处在于，它强调了 BNC 生产中的遗传修饰可能性，以克服现有障碍，并为大规模生产开辟可行的途径，适用于实际应用。本综述重点介绍了 BNC 的各种生产途径、其性质和应用，特别是在食品、个人护理、生物医学和电子行业的主要进展。
