月经过少的青春期女孩的内分泌特征。

Endocrinologic features of oligomenorrheic adolescent girls.

作者信息

Siegberg R, Nilsson C G, Stenman U H, Widholm O

出版信息

Fertil Steril. 1986 Nov;46(5):852-7.

Abstract

The plasma concentrations of sex hormones were measured in 45 oligomenorrheic and 28 regularly menstruating adolescent girls. Testosterone, androstenedione, dehydroepiandrosterone, dehydroepiandrosterone-sulfate, estradiol, progesterone, luteinizing hormone, follicle-stimulating hormone, prolactin, and sex hormone-binding globulin levels were determined in blood samples collected during one menstrual cycle. The oligomenorrheic girls had significantly higher concentrations of luteinizing hormone, androstenedione, dehydroepiandrosterone-sulfate, and free testosterone than regularly menstruating girls. Sex hormone-binding globulin concentrations were significantly lower in the oligomenorrheic group. The oligomenorrheic girls were not obese. Signs of acne or hirsutism were absent or mild. Sixty-six percent of the oligomenorrheic cycles were ovulatory. The significance of the hormonal findings is discussed.

摘要

对45名月经稀发的青春期女孩和28名月经周期正常的青春期女孩的血浆性激素浓度进行了测量。在一个月经周期内采集的血样中测定了睾酮、雄烯二酮、脱氢表雄酮、硫酸脱氢表雄酮、雌二醇、孕酮、促黄体生成素、促卵泡生成素、催乳素和性激素结合球蛋白水平。月经稀发的女孩促黄体生成素、雄烯二酮、硫酸脱氢表雄酮和游离睾酮的浓度显著高于月经周期正常的女孩。月经稀发组的性激素结合球蛋白浓度显著较低。月经稀发的女孩并不肥胖。痤疮或多毛症的体征不存在或较轻。66%的月经稀发周期有排卵。文中讨论了激素检测结果的意义。