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在接受机器人辅助腹腔镜根治性前列腺切除术的患者中,采用呼气末正压通气的招募手法对肺顺应性的影响。

The effects of a recruitment manoeuvre with positive end-expiratory pressure on lung compliance in patients undergoing robot-assisted laparoscopic radical prostatectomy.

机构信息

Department of Anesthesiology and Pain Medicine, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.

出版信息

J Clin Monit Comput. 2020 Apr;34(2):303-310. doi: 10.1007/s10877-019-00306-y. Epub 2019 Apr 9.

Abstract

The effects of a recruitment manoeuvre (RM) with positive end-expiratory pressure (PEEP) on lung compliance (C) are not well characterised in robot-assisted laparoscopic radical prostatectomy (RARP). Patients were allocated to group R (n = 10; with an RM) or C (n = 9; without an RM). An RM involved sustained inflation of 30 cmHO for 30 s. The lungs were ventilated with volume-controlled ventilation with tidal volume of 7 mL kg of predicted body weight and fraction of inspired oxygen of 0.5. End-tidal carbon dioxide pressure was maintained at normocapnia. Patients were in the horizontal lithotomy position (pre-op). After pneumoperitoneum, patients underwent RARP in a steep Trendelenburg lithotomy position at a PEEP level of 0 cmHO (RARP0). An RM was used in the R group but not in the C group. Patients were then ventilated with 5 cmHO PEEP for 1 h after RARP0 (RARP5.1) and 2 h after RARP0 (RARP5.2). Oesophageal pressure and airway pressure were measured for calculating C and chest wall compliance. C significantly decreased from pre-op to RARP0 and did not significantly increase from RARP0 to RARP5.1 and RARP5.2 in either group. C differed significantly between groups at RARP5.1 and RARP5.2 (103 ± 30 vs. 68 ± 11 mL cm HO and 106 ± 35 vs. 72 ± 9 mL cm HO; P < 0.05). In patients undergoing RARP, with the addition of RM, the C was effectively increased from the horizontal lithotomy position to the steep Trendelenburg lithotomy position under pneumoperitoneum.

摘要

在机器人辅助腹腔镜根治性前列腺切除术(RARP)中,充气招法(RM)加呼气末正压(PEEP)对肺顺应性(C)的影响尚未得到很好的描述。患者被分配到 R 组(n=10;采用 RM)或 C 组(n=9;不采用 RM)。RM 涉及持续充气 30cmH2O 30 秒。肺采用容量控制通气,潮气量为预测体重的 7ml/kg,吸入氧分数为 0.5。呼气末二氧化碳压力保持正常碳酸血症。患者处于水平截石位(术前)。气腹后,患者在 0cmH2O 呼气末正压(RARP0)下以陡峭的特伦德伦伯卧位接受 RARP。R 组使用 RM,但 C 组不使用。然后,患者在 RARP0 后 1 小时(RARP5.1)和 RARP0 后 2 小时(RARP5.2)以 5cmH2O PEEP 通气。测量食管压和气道压以计算 C 和胸壁顺应性。两组患者的 C 值均从术前降至 RARP0,且从 RARP0 至 RARP5.1 和 RARP5.2 均无明显增加。两组患者在 RARP5.1 和 RARP5.2 时 C 值差异显著(103±30 vs. 68±11mL·cmH2O 和 106±35 vs. 72±9mL·cmH2O;P<0.05)。在接受 RARP 的患者中,在充气招法(RM)的基础上,C 值从水平截石位有效地增加到气腹下的陡峭特伦德伦伯卧位。

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