Department of Cell Biology and Physiology, Washington University School of Medicine , St. Louis, Missouri.
Institut Curie, PSL Research University, CNRS, Paris , France.
Physiology (Bethesda). 2019 May 1;34(3):169-177. doi: 10.1152/physiol.00045.2018.
Extracellular vesicles (EVs), cell-derived membrane structures, are secreted after fusion of endosomes with the plasma membrane (exosomes) or shed from the plasma membrane (microvesicles). EVs play a key role both in physiological balance and homeostasis and in disease processes by their ability to participate in intercellular signaling and communication.
细胞外囊泡（EVs）是细胞来源的膜结构，在内涵体与质膜融合后（外泌体）或从质膜脱落（微泡）时被分泌出来。EVs 通过参与细胞间信号传递和通讯的能力，在生理平衡和内稳态以及疾病过程中发挥着关键作用。
