Sports Research Center, Hosei University, Tokyo, Japan.
Faculty of Sport and Health Science, Ritsumeikan University, Shiga, Japan.
Scand J Med Sci Sports. 2019 Aug;29(8):1115-1120. doi: 10.1111/sms.13434. Epub 2019 Apr 29.
Resistance exercise impairs endothelial function. Therefore, it is of paramount importance to devise an effective strategy for restoring endothelial function after resistance exercise. Herein, we tested the hypothesis that resistance exercise-induced endothelial dysfunction would be restored by low-to-moderate intensity cycling. Seventeen young healthy subjects completed two randomized experimental trials: (a) resistance exercise only trial; and (b) cycling after the resistance exercise trial. Following baseline brachial artery flow-mediated dilation (FMD), subjects performed the resistance exercise. Following the resistance exercise, they were asked to rest in the supine position for the assessments of FMD. Subjects in the resistance exercise only trial maintained this supine position for 60 minutes, whereas those in the other trial cycled for 10 minutes after the resistance exercise trial. Subjects were again asked to rest in the supine position after cycling. Then FMD were repeated at 30 and 60 minutes after the resistance exercise in both trials. In the resistance exercise only trial, the increased blood flow and shear rate were disappeared after 1 hour of resting in the supine position, but were maintained in those in the cycling after the resistance trial due to subsequent cycling. Both trials caused a significant impairment in FMD at 10 minutes after the resistance exercise (P < 0.05). This decline was sustained for 60 minutes in the resistance exercise only trial. However, the impaired FMD was restored in the cycling after the resistance exercise trial. In conclusion, impaired endothelial function after the resistance exercise can be restored with 10 minutes of low-to-moderate intensity cycling.
抗阻运动可损害血管内皮功能。因此，制定一种有效的策略来恢复抗阻运动后的内皮功能至关重要。在此，我们检验了假设，即低中强度的循环运动将恢复抗阻运动引起的血管内皮功能障碍。17 名年轻健康的受试者完成了两项随机对照试验：（a）仅抗阻运动试验；（b）抗阻运动后进行循环运动试验。在肱动脉血流介导的舒张（FMD）的基线测量后，受试者进行抗阻运动。在抗阻运动后，他们被要求平卧位休息以评估 FMD。仅抗阻运动组的受试者在平卧位保持 60 分钟，而另一组在抗阻运动后进行 10 分钟的循环运动。受试者在循环运动后再次平卧位休息。然后在两项试验中，在抗阻运动后 30 分钟和 60 分钟重复 FMD 测量。在仅抗阻运动组中，平卧位休息 1 小时后，血流和剪切率增加的情况消失，但在抗阻运动后进行循环运动组中保持不变，因为随后进行了循环运动。在抗阻运动后 10 分钟，这两项试验均显著损害了 FMD（P<0.05）。仅抗阻运动组的这种下降持续了 60 分钟。然而，在抗阻运动后进行循环运动试验可恢复受损的 FMD。总之，抗阻运动后内皮功能的受损可以通过 10 分钟的低中强度循环运动来恢复。
