Psoriasis Research Center, Hamadan University of Medical Sciences (HUMS), Hamadan, Iran.
Research Center for Behavioral Disorders and Substance Abuse, Hamadan University of Medical Sciences (HUMS), Hamadan, Iran.
Neuropsychobiology. 2019;78(2):95-103. doi: 10.1159/000499135. Epub 2019 Apr 10.
Individuals with lichen planopilaris (LPP) typically present with hair loss and an irritated scalp, with signs and symptoms such as itching, erythema, scaling, and burning. Both hair loss and reddened skin may be visible also for other people. Therefore, it is conceivable that individuals with LPP might report a lower mental health status. Accordingly, in the present study, we compared dimensions of mental health between individuals with LPP and healthy controls.
A total of 38 individuals with LPP (mean age: 38.24 years, 47.4% females) and 58 gender- and age-matched controls took part in this study. They completed questionnaires covering dimensions of quality of life and self-esteem; experts rated participants' symptoms of depression and anxiety. Furthermore, dermatologists reported on the illness duration, the LPP activity index, and the severity of alopecia.
Compared to healthy controls, individuals with LPP reported lower scores of self-esteem, physical functioning, and mental health and higher scores of role limitations (physical and emotional). Likewise, experts rated higher depression scores in individuals with LPP compared to controls. In individuals with LPP, a higher LPP disease activity and a higher severity of hair loss were associated with higher depression and lower quality-of-life scores. Further, a higher LPP activity index, a lower self-esteem, and higher anxiety scores predicted a poorer quality of life, while illness duration was statistically unrelated.
Compared to controls, and irrespectively of the illness duration, individuals with LPP reported a lower quality of life and a lower self-esteem, and experts' ratings observed higher scores of depression. Experts treating individuals with LPP might pay special attention to the individuals' mental health status.
患有瘢痕性类狼疮（LPP）的个体通常表现为脱发和头皮发炎，其症状和体征包括瘙痒、红斑、鳞屑和烧灼感。脱发和发红的皮肤也可能对其他人可见。因此，可以想象 LPP 患者的心理健康状况可能较低。因此，在本研究中，我们比较了 LPP 患者和健康对照组之间心理健康的各个方面。
共有 38 名 LPP 患者（平均年龄：38.24 岁，47.4%为女性）和 58 名性别和年龄匹配的对照者参加了这项研究。他们完成了涵盖生活质量和自尊各个方面的问卷；专家评估了参与者的抑郁和焦虑症状。此外，皮肤科医生报告了疾病持续时间、LPP 活动指数和脱发严重程度。
与健康对照组相比，LPP 患者的自尊、身体机能和心理健康评分较低，角色限制（身体和情绪）评分较高。同样，与对照组相比，专家对 LPP 患者的抑郁评分较高。在 LPP 患者中，较高的 LPP 疾病活动度和较高的脱发严重程度与较高的抑郁和较低的生活质量评分相关。此外，较高的 LPP 活动指数、较低的自尊和较高的焦虑评分预示着较差的生活质量，而疾病持续时间与生活质量无关。
与对照组相比，LPP 患者无论疾病持续时间如何，报告的生活质量和自尊较低，专家评估的抑郁评分较高。治疗 LPP 患者的专家可能特别关注患者的心理健康状况。
