Department of Welfare, National Institute for Health and Welfare, Mannerheimintie 166, PL 30, 00271, Helsinki, Finland.
Department of Public Health Solutions, National Institute for Health and Welfare, Mannerheimintie 166, PL 30, 00271, Helsinki, Finland.
BMC Public Health. 2019 Apr 11;19(1):391. doi: 10.1186/s12889-019-6698-0.
Persons of African and Middle-Eastern origin living in European countries have a high prevalence of type 2 diabetes, accompanied by high prevalence of obesity among women but not always among men. The aim of this study was to examine whether there are differences in the association between anthropometric measures and glucose levels measured with glycated haemoglobin and fasting blood glucose among persons of migrant origin in Finland.
Cross-sectional population-based data of the 30-64 year-old participants in the health examination of the Migrant Health and Wellbeing Study was used, selecting persons without diabetes (Russian origin n = 293, Somali origin n = 184, Kurdish origin n = 275). The reference group were non-diabetic participants in the Health 2011 Survey (n = 653), representative of the general Finnish population. Anthropometric measures included body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR) and waist-to-hip ratio (WHR, available for Maamu Study participants only).
Depending on whether continuous or categorical anthropometric measures were used, age, sex and anthropometrics explained 13-18% of variation in HbA1c among persons of Russian origin, 5-10% among persons of Somali origin, 1-3% among persons of Kurdish origin and 11-13% among the general population. Also depending on whether continuous or categorical anthropometric measures were used, age, sex and anthropometrics explained 13-19% of variation in fasting blood glucose among persons of Russian origin, 15-20% among persons of Somali origin, 13-17% among persons of Kurdish origin and 16-17% among the general population. With exception for BMI, strength of the association between continuous anthropometric measures and HbA1c was significantly lower among persons of Kurdish origin compared with the general Finnish population (p = 0.044 for WC and p = 0.040 for WHtR).
A low degree of association between anthropometric measures and HbA1c was observed among persons of Kurdish origin. Findings of this study suggest caution is warranted when using HbA1c as a screening tool for glucose impairment among persons without diabetes in populations of diverse origin.
生活在欧洲国家的非裔和中东裔人群 2 型糖尿病患病率较高，女性肥胖率也较高，但男性肥胖率并非总是如此。本研究旨在探讨芬兰移民人群中，人体测量指标与糖化血红蛋白和空腹血糖之间的相关性是否存在差异。
本研究使用了 30-64 岁参加移民健康与幸福感研究健康检查的参与者的横断面人群基础数据，选择无糖尿病的参与者（俄罗斯裔 n=293 人，索马里裔 n=184 人，库尔德裔 n=275 人）。对照组为 2011 年健康调查（n=653 人）中无糖尿病的参与者，代表芬兰一般人群。人体测量指标包括体重指数（BMI）、腰围（WC）、腰高比（WHtR）和腰臀比（WHR，仅适用于 Maamu 研究参与者）。
根据连续或分类人体测量指标的使用情况，年龄、性别和人体测量指标解释了俄罗斯裔人群中糖化血红蛋白变异的 13-18%，索马里裔人群中变异的 5-10%，库尔德裔人群中变异的 1-3%，以及一般人群中变异的 11-13%。同样，根据连续或分类人体测量指标的使用情况，年龄、性别和人体测量指标解释了俄罗斯裔人群中空腹血糖变异的 13-19%，索马里裔人群中变异的 15-20%，库尔德裔人群中变异的 13-17%，以及一般人群中变异的 16-17%。除 BMI 外，与一般芬兰人群相比，库尔德裔人群中连续人体测量指标与糖化血红蛋白之间的关联强度显著较低（WC 为 p=0.044，WHtR 为 p=0.040）。
在库尔德裔人群中，人体测量指标与糖化血红蛋白之间的相关性较低。本研究结果表明，在不同起源人群中，使用糖化血红蛋白作为无糖尿病人群血糖受损的筛查工具时应谨慎。
