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2 型糖尿病住院患者传统和非传统人体测量指数与心血管代谢危险因素的关系：一项横断面研究。

Associations between traditional and non-traditional anthropometric indices and cardiometabolic risk factors among inpatients with type 2 diabetes mellitus: a cross-sectional study.

机构信息

Abadan University of Medical Sciences, Abadan, Khuzestan, Iran.

Department of Clinical Biochemistry, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Khuzestan, Iran.

出版信息

J Int Med Res. 2021 Oct;49(10):3000605211049960. doi: 10.1177/03000605211049960.

DOI:10.1177/03000605211049960
PMID:34657502
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8524710/
Abstract

OBJECTIVE

We aimed to evaluate whether traditional and non-traditional adiposity indicators are associated with cardiometabolic risk factors among adult patients with type 2 diabetes mellitus (DM).

METHODS

In this cross-sectional study among 240 inpatients with type 2 DM, we determined traditional anthropometric indicators including body mass index, waist circumference, hip circumference (HC), waist-to-hip ratio (WHR), waist-to-height ratio, and non-traditional anthropometric indicators including lipid accumulation product (LAP), visceral adiposity index (VAI), deep abdominal adipose tissue (DAAT), and Després indices. Lipid profile, fasting blood glucose, glycated hemoglobin (HbA1c), systolic blood pressure (SBP), and diastolic blood pressure (DBP) were measured to evaluate cardiometabolic parameters.

RESULTS

In overweight patients, DAAT was positively correlated with total triglycerides. LAP was negatively correlated with serum HDL-C levels. WHR and DAAT were associated with total triglycerides, HbA1c, total cholesterol, total cholesterol/HDL-C, and total triglycerides/HDL-C, after adjustment for age and duration of disease. VAI, DAAT, LAP, and Després index were significant determinants of lipid profile and SBP.

CONCLUSION

Traditional and non-traditional anthropometric indices are associated with cardiometabolic risk factors in patients with type 2 DM.

摘要

目的

本研究旨在评估传统和非传统肥胖指标与 2 型糖尿病（DM）成年患者的心血管代谢危险因素之间的相关性。

方法

在这项横断面研究中，共纳入 240 名 2 型 DM 住院患者，我们测定了传统的人体测量学指标，包括体重指数、腰围、臀围（HC）、腰臀比（WHR）、腰高比，以及非传统的人体测量学指标，包括脂堆积产物（LAP）、内脏脂肪指数（VAI）、深腹内脂肪组织（DAAT）和德斯普雷斯指数。测量血脂谱、空腹血糖、糖化血红蛋白（HbA1c）、收缩压（SBP）和舒张压（DBP）以评估心血管代谢参数。

结果

在超重患者中，DAAT 与总三酰甘油呈正相关。LAP 与血清高密度脂蛋白胆固醇（HDL-C）水平呈负相关。WHR 和 DAAT 与总三酰甘油、HbA1c、总胆固醇、总胆固醇/HDL-C 和总三酰甘油/HDL-C 呈正相关，校正年龄和疾病持续时间后。VAI、DAAT、LAP 和 Després 指数是血脂谱和 SBP 的重要决定因素。

结论

传统和非传统人体测量学指标与 2 型 DM 患者的心血管代谢危险因素相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa7a/8524710/8d488438a45c/10.1177_03000605211049960-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa7a/8524710/8d488438a45c/10.1177_03000605211049960-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa7a/8524710/8d488438a45c/10.1177_03000605211049960-fig1.jpg

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