Botchlett Rachel, Wu Chaodong
Pinnacle Clinical Research, Live Oak, TX, 78233, USA.
Department of Nutrition and Food Science, Texas A&M University, College Station, TX, 77843, USA.
J Diabetes Mellit Metab Syndr. 2018;3:10-25. doi: 10.28967/jdmms.2018.01.18002. Epub 2018 Sep 19.
Healthy nutrition is essential for prevention of disease and for maintenance or promotion of health; although healthy nutrition remains to be precisely defined. Over the past several decades, various types of nutrients have been functionally validated and considered as critical components of healthy nutrition, which commonly include fiber-enriched carbohydrates, mono- or poly-unsaturated fatty acids, essential amino acids, and certain micronutrients. When managing obesity and obesity-associated metabolic diseases, much attention has been paid to the content of nutrients that is considered as healthy nutrition. Accumulating evidence also suggests that nutrient composition could be more important than the content of individual nutrients in the context of reducing body weight and obesity-associated risk for metabolic diseases. Consistently, it would be more important to focus on diet with differences in nutrient ratios rather than individual type(s) of nutrients in terms of managing obesity and metabolic diseases. In this review, recent advances in dietary management of obesity and obesity-related metabolic diseases have been discussed. This review also has highlighted several specific diet compositions and their differences in managing hypertension, type 2 diabetes, and non-alcoholic fatty liver disease.
健康营养对于疾病预防以及健康维持或促进至关重要;尽管健康营养仍有待精确界定。在过去几十年里,各类营养素已在功能上得到验证,并被视为健康营养的关键组成部分,通常包括富含纤维的碳水化合物、单不饱和或多不饱和脂肪酸、必需氨基酸以及某些微量营养素。在管理肥胖症及与肥胖相关的代谢性疾病时,人们十分关注被视为健康营养的营养素含量。越来越多的证据还表明,在减轻体重及降低与肥胖相关的代谢性疾病风险方面,营养素组成可能比单一营养素的含量更为重要。同样,在管理肥胖症和代谢性疾病方面,关注营养素比例不同的饮食比关注单一类型的营养素更为重要。在这篇综述中,讨论了肥胖症及与肥胖相关的代谢性疾病饮食管理的最新进展。本综述还强调了几种特定的饮食组成及其在管理高血压、2型糖尿病和非酒精性脂肪性肝病方面的差异。