Department of Orthopedic, Traumatology and Reconstructive Surgery, PERCY Military Teaching Hospital, 101 Avenue Henri Barbusse, 92141, Clamart, France.
Department of Surgery, French Military Health Service Academy, École du Val-de-Grâce, Paris, France.
Int Orthop. 2019 Dec;43(12):2671-2680. doi: 10.1007/s00264-019-04329-7. Epub 2019 Apr 11.
Treatment of war wounds is based on a sequential surgical strategy, which frequently faces therapeutic failures, which then burden the final functional result. The aim of this study was to identify risk factors of failure of the different treatments to prevent the therapeutic failure.
A monocentric case-control study was done on French war-wounded soldiers treated for an open fracture caused by an invasive war weapon. The primary end point was the treatment failure three months after the injury. The risk factors of failure studied were the traumatic mechanism, the general and local lesional assessment, and the surgery performed.
Between January 1, 2004 and December 31, 2016, 57 soldiers were included, with an average follow-up of 3.42 years. On 81 limb segments studied, the most injured segment was the leg (37.0%). A vital or urgent surgery requirement (OR = 1.56; p = 0.02) and bone loss substance (OR = 5.45; CI95% = 1.54-20.09) were risk factors of failure for limb salvage treatment. Improvised explosive device traumatic mechanism (OR = 1.56; p = 0.02) and the persistence of surgical site contamination after two debridement procedures (OR = 1.20; p = 0.04) were risk factors of failure for amputation procedures.
Two main risk factors of treatment failure are highlighted: those in relation to traumatic mechanisms and general lesional assessment and those in relation to surgical site conditions. There is no over risk of failure in relation to surgical procedure and treatment.
战伤的治疗基于序贯手术策略,但该策略常面临治疗失败,进而影响最终的功能结果。本研究旨在明确不同治疗方法失败的风险因素,以预防治疗失败。
对法国因侵袭性战争武器导致开放性骨折的战伤士兵进行了一项单中心病例对照研究。主要终点为损伤后 3 个月的治疗失败。研究的失败风险因素包括创伤机制、全身和局部损伤评估以及手术治疗。
2004 年 1 月 1 日至 2016 年 12 月 31 日,共纳入 57 名士兵,平均随访 3.42 年。在 81 个肢体节段中,受伤最多的是腿部(37.0%)。需要紧急或紧急手术(OR=1.56;p=0.02)和骨质丢失(OR=5.45;95%CI95%=1.54-20.09)是保肢治疗失败的风险因素。简易爆炸装置创伤机制(OR=1.56;p=0.02)和两次清创后手术部位仍存在污染(OR=1.20;p=0.04)是截肢治疗失败的风险因素。
突出了两个主要的治疗失败风险因素:与创伤机制和全身损伤评估相关的因素,以及与手术部位情况相关的因素。手术方法和治疗不存在过度失败的风险。