Smith Andrew Dennis, Porter Kristin K, Elkassem Asser Abou, Sanyal Rupan, Lockhart Mark E
Department of Radiology, University of Alabama at Birmingham, 619 19th St S, Birmingham, AL 35249.
AJR Am J Roentgenol. 2019 Jul;213(1):77-89. doi: 10.2214/AJR.19.21144. Epub 2019 Apr 11.
The purpose of this article is to discuss quantitative methods of CT, MRI, and ultrasound (US) for noninvasive staging of hepatic fibrosis. Hepatic fibrosis is the hallmark of chronic liver disease (CLD), and staging by random liver biopsy is invasive and prone to sampling errors and subjectivity. Several noninvasive quantitative imaging methods are under development or in clinical use. The accuracy, precision, technical aspects, advantages, and disadvantages of each method are discussed. The most promising methods are the liver surface nodularity score using CT and measurement of liver stiffness using MR elastography or US elastography.
本文旨在探讨CT、MRI和超声（US）用于肝纤维化无创分期的定量方法。肝纤维化是慢性肝病（CLD）的标志，通过随机肝活检进行分期具有侵入性，且容易出现取样误差和主观性。几种无创定量成像方法正在开发中或已应用于临床。本文讨论了每种方法的准确性、精确性、技术方面、优点和缺点。最有前景的方法是使用CT的肝表面结节评分以及使用磁共振弹性成像或超声弹性成像测量肝脏硬度。
