Peduto Tiziana, Cillo Francesco, Nappa Paola, Delfino Mario, Fabbrocini Gabriella, Ferrillo Maria
Department of Dermatology, University of Naples Federico II, Via Pansini 5, 80131 Napoli, Italy.
Open Access Maced J Med Sci. 2019 Mar 27;7(6):1021-1024. doi: 10.3889/oamjms.2019.162. eCollection 2019 Mar 30.
Kaposi's sarcoma (KS) is a tumour of endothelial, blood and lymphatic cells, caused by an infection with human herpesvirus-8 (HHV-8). The skin lesions of KS, especially of the classical or Mediterranean variant (CKS), are represented by red-purple macules, plaques and nodules, localised mainly on the extremities.
This case series intend to describe multifocal atypical kaposian manifestations in two HIV negative subjects, affected by CKS, treated with successful chemotherapy.
Although atypical manifestations are extremely rare events, we suggest an accurate, objective examination because a prompt diagnosis can lead to a vital intervention in the patient's health and sometimes to the identification of the disease itself.
卡波西肉瘤(KS)是一种由人类疱疹病毒8型(HHV - 8)感染引起的内皮细胞、血液和淋巴细胞肿瘤。KS的皮肤病变,尤其是经典型或地中海型(CKS)的皮肤病变,表现为红紫色斑疹、斑块和结节,主要位于四肢。
本病例系列旨在描述两名受CKS影响的HIV阴性患者出现的多灶性非典型卡波西表现,他们接受化疗后取得了成功。
尽管非典型表现极为罕见,但我们建议进行准确、客观的检查,因为及时诊断可对患者健康进行重要干预,有时还能识别疾病本身。