Eichelmann A-K, Pascher A
Klinik für Allgemein‑, Viszeral- und Transplantationschirurgie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, Gebäude W1, 48149, Münster, Deutschland.
Chirurg. 2019 Jul;90(7):537-541. doi: 10.1007/s00104-019-0957-6.
Gastrointestinal surgery is still associated with a relevant morbidity with the intestinal microbiome being of high importance in the pathogenesis of infectious complications. Various approaches, such as mechanical bowel preparation (MBP) with or without administration of oral antibiotics, fasting or dietary supplements aim at modulating the intestinal flora.
This review summarizes the current literature pertinent to the influence of preoperative bowel conditioning on postoperative morbidity.
A literature search was performed using the mentioned keywords with a focus on recent meta-analyses.
Bowel conditioning reduces postoperative infectious complications. Promising approaches are MBP plus administration of oral antibiotics, dietary supplements aiming at stabilization of the intestinal flora as well as the screening for and equilibration of malnutrition. The use of MBP as monotherapy without antibiotics should no longer be considered part of the clinical routine.
胃肠道手术仍伴有一定的发病率,肠道微生物群在感染性并发症的发病机制中具有重要意义。各种方法,如使用或不使用口服抗生素的机械肠道准备(MBP)、禁食或膳食补充剂,旨在调节肠道菌群。
本综述总结了当前与术前肠道调理对术后发病率影响相关的文献。
使用上述关键词进行文献检索,重点关注近期的荟萃分析。
肠道调理可减少术后感染性并发症。有前景的方法包括MBP加口服抗生素、旨在稳定肠道菌群的膳食补充剂以及营养不良的筛查和平衡。仅使用MBP而不使用抗生素的单一疗法不应再被视为临床常规的一部分。