Department of Nutrition Sciences, Drexel University, Philadelphia, PA, USA.
Pharmacy Specialist in Clinical Nutrition, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Curr Nutr Rep. 2019 Jun;8(2):92-98. doi: 10.1007/s13668-019-0273-2.
The interactions between nutrition and medication can be numerous with potential impact on health outcomes. Several subtypes of drug-nutrition interactions exist. Each of these interaction subtypes may influence patients receiving medication for neurologic disorders. After defining drug-nutrition interactions, this review will describe the various types using a handful of widely used central nervous system agents as examples.
Medication may be the object of interactions perpetrated by a specific meal, a food component, a nutrient, or nutrition status thereby altering drug disposition and clinical effect. On the other hand, drugs can influence nutrition status generally or the status of specific nutrients by any number of mechanisms. Individuals using medication for neurologic disorders are at risk for drug-nutrition interactions of all types.
营养与药物之间的相互作用可能很多，对健康结果有潜在影响。存在几种亚型的药物-营养相互作用。这些相互作用的每个亚型都可能影响接受治疗神经系统疾病的患者。在定义药物-营养相互作用后，本综述将使用一些广泛使用的中枢神经系统药物作为示例来描述各种类型。
药物可能成为特定膳食、食物成分、营养素或营养状况相互作用的对象，从而改变药物处置和临床效果。另一方面，药物可以通过多种机制影响营养状况或特定营养素的状况。使用药物治疗神经系统疾病的个体存在各种类型的药物-营养相互作用的风险。
