Department of Neurology, Bozok University, Faculty of Medicine, Yozgat, Turkey.
Department of Psychiatry, Bozok University, Faculty of Medicine, Yozgat, Turkey.
Epilepsy Behav. 2019 May;94:233-238. doi: 10.1016/j.yebeh.2019.03.027. Epub 2019 Apr 9.
The objective of this study was to evaluate the spouses of people with epilepsy with and without a history of seizures during sleep in terms of depression, anxiety, and sleep quality.
This prospective, cross-sectional study was conducted in three groups of 18-55 year olds, who were at least primary school graduates. The 1st group consisted of healthy spouses of 30 healthy volunteers with age and sex matched with the other groups. The 2nd group comprised spouses of 30 people with epilepsy who had been married for at least one year and had no history of seizures during sleep. The 3rd group consisted of spouses of 30 people with epilepsy who had been married for at least one year and had a history of at least one seizure during sleep in the course of the previous year. The questionnaire including demographic data, Pittsburgh Sleep Quality Index (PSQI), Beck Depression Inventory (BDI), and the Beck Anxiety Inventory (BAI) was applied to all participants.
The mean age of the 1st group was 35.07 ± 8.33 years, that of the 2nd group was 36.47 ± 7.63 years, and that of the 3rd group was 35.33 ± 6.05 years. There was no significant age difference between the groups (p = 0.740). The depression scores of the 2nd and the 3rd groups were significantly higher than that of the 1st group (p < 0.001, for both). The anxiety scores of the 3rd group were significantly higher than those of the 1st and the 2nd groups (p < 0.001 and p = 0.001, respectively). Thirty percent (n = 9) of the 1st group, 40% (n = 12) of the 2nd group, and 70% (n = 21) of the 3rd group had poor sleep quality. The sleep disorder rate in the 3rd group was significantly higher than in the 1st and the 2nd groups (p = 0.002 and p = 0.020, respectively). When the PSQI subscales were examined, the sleep quality, sleep latency, usual sleep efficiency, daytime dysfunction, and the total sleep total score were significantly higher in the 3rd group than the 1st and the 2nd groups. The patients in the third group had significantly higher scores of sleep duration, sleep disturbance, and sleep medication use than those in the 1st group.
We found out that the PSQI score, which reflected the sleep quality, was poor in the spouses of people with epilepsy, who had seizures during sleep. To the best of our knowledge, these findings are the first in the literature on this subject.
本研究旨在评估睡眠中伴发或不伴发癫痫发作的癫痫患者配偶的抑郁、焦虑和睡眠质量。
本前瞻性、横断面研究纳入了三组年龄在 18-55 岁之间、至少完成小学教育的参与者。第 1 组为 30 名健康志愿者的健康配偶，与其他组在年龄和性别上相匹配。第 2 组为 30 名婚后至少 1 年且无睡眠中癫痫发作史的癫痫患者配偶。第 3 组为 30 名婚后至少 1 年且在过去 1 年内至少有 1 次睡眠中癫痫发作史的癫痫患者配偶。所有参与者均填写包括人口统计学数据、匹兹堡睡眠质量指数（PSQI）、贝克抑郁量表（BDI）和贝克焦虑量表（BAI）在内的问卷。
第 1 组的平均年龄为 35.07±8.33 岁，第 2 组为 36.47±7.63 岁，第 3 组为 35.33±6.05 岁。组间年龄差异无统计学意义（p=0.740）。第 2 组和第 3 组的抑郁评分显著高于第 1 组（p<0.001，均）。第 3 组的焦虑评分显著高于第 1 组和第 2 组（p<0.001 和 p=0.001）。第 1 组中有 30%（n=9）、第 2 组中有 40%（n=12）和第 3 组中有 70%（n=21）的睡眠质量较差。第 3 组的睡眠障碍发生率显著高于第 1 组和第 2 组（p=0.002 和 p=0.020）。当检查 PSQI 各亚量表时，第 3 组的睡眠质量、睡眠潜伏期、通常的睡眠效率、日间功能障碍和总睡眠总分显著高于第 1 组和第 2 组。与第 1 组相比，第 3 组的睡眠时间、睡眠障碍和睡眠药物使用评分显著更高。
我们发现，睡眠中伴发癫痫发作的癫痫患者配偶的匹兹堡睡眠质量指数（PSQI）评分反映了较差的睡眠质量。据我们所知，这些发现是该主题文献中的首次发现。
