Yozgat City Hospital, Department of Neurology, Yozgat, Turkey.
Kayseri City Hospital, Department of Neurology, Kayseri, Turkey.
Arq Neuropsiquiatr. 2021 May;79(5):420-428. doi: 10.1590/0004-282X-ANP-2020-0207.
Psychiatric problems and sleep disturbances are comorbidities that are frequently encountered among people with epilepsy. However, their presence among the spouses of peoples with epilepsy remains to be elucidated.
The objective of this study was to evaluate the spouses of people with epilepsy (PWE), with and without a history of seizures during sleep, in terms of depression, anxiety and sleep quality.
This prospective, cross-sectional study was conducted in three groups of 18 to 65-year-olds. Group 1 consisted of healthy spouses of 127 healthy volunteers without any known neurological disease; group 2 comprised spouses of 63 PWE who had no history of seizure during sleep; and group 3 consisted of spouses of 63 PWE who had a history of at least one seizure during sleep in the course of the previous year. Questionnaires seeking demographic data and the Pittsburgh Sleep Quality Index (PSQI), Beck Depression Inventory and Beck Anxiety Inventory were applied to all participants.
The depression scores of the group of spouses of PWE were higher than those of the control group and were higher in group 3 than in group 2 (p = 0.017). The anxiety scores of the group of spouses of PWE were significantly higher than those of the control group, but no difference in anxiety scores was found between group 2 and group 3 (p = 0.170). The mean PSQI score of group 3 was higher than that of group 2 (p = 0.029). However, regression analyses did not show any difference between these groups.
We found that the PSQI scores, which reflected sleep quality, were higher among the spouses of PWE who had seizures during sleep and who had more severe epilepsy.
精神疾病和睡眠障碍是癫痫患者常见的共病，但癫痫患者配偶中是否存在这些问题仍需阐明。
本研究旨在评估有或无睡眠中癫痫发作史的癫痫患者配偶的抑郁、焦虑和睡眠质量。
本前瞻性、横断面研究纳入了三组年龄在 18 至 65 岁之间的人群。第 1 组为 127 名无任何已知神经疾病的健康志愿者的健康配偶；第 2 组为无睡眠中癫痫发作史的 63 名癫痫患者配偶；第 3 组为过去 1 年中有至少 1 次睡眠中癫痫发作史的 63 名癫痫患者配偶。所有参与者均接受了问卷调查，包括人口统计学数据、匹兹堡睡眠质量指数（PSQI）、贝克抑郁量表和贝克焦虑量表。
癫痫患者配偶组的抑郁评分高于对照组，且第 3 组高于第 2 组（p = 0.017）。癫痫患者配偶组的焦虑评分明显高于对照组，但第 2 组与第 3 组之间的焦虑评分无差异（p = 0.170）。第 3 组的 PSQI 平均评分高于第 2 组（p = 0.029）。然而，回归分析并未显示这些组之间存在差异。
我们发现，睡眠中发作且癫痫更严重的癫痫患者配偶的 PSQI 评分（反映睡眠质量）更高。
