Tsujimoto Takashi, Hosoda Nao, Uyama Hiroshi
Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Yamadaoka 2-1, Suita, Osaka 565-0871, Japan.
Polymers (Basel). 2016 Feb 29;8(3):66. doi: 10.3390/polym8030066.
This study deals with the fabrication of biodegradable porous materials from bacterial polyester, poly(3-hydroxybutyrate--3-hydroxyhexanoate) (P3HB3HH), via thermally induced phase separation. P3HB3HH monoliths with topological porous structure were prepared by dissolution of P3HB3HH in dimethyl sulfoxide (DMSO) at 85 °C and subsequent quenching. The microstructure of the resulting P3HB3HH monoliths was changed by the P3HB3HH concentration of the polymer solution. Differential scanning calorimetry and polarized optical microscope analysis revealed that the P3HB3HH monoliths crystallized during phase separation and the subsequent aging. The mechanical properties, such as compression modulus and stress, of the monoliths depended on the 3-hydroxyhexanoate content of P3HB3HH. Furthermore, the P3HB3HH monolith absorbed linseed oil in preference to water in a plant oil⁻water mixture. In combination with the biodegradable character of P3HB3HH, the present study is expected to contribute to the development of bio-based materials.
本研究涉及通过热致相分离法由细菌聚酯聚（3-羟基丁酸酯-3-羟基己酸酯）（P3HB3HH）制备可生物降解的多孔材料。通过在85℃下将P3HB3HH溶解于二甲基亚砜（DMSO）中并随后骤冷，制备出具有拓扑多孔结构的P3HB3HH整料。所得P3HB3HH整料的微观结构因聚合物溶液中P3HB3HH的浓度而改变。差示扫描量热法和偏光显微镜分析表明，P3HB3HH整料在相分离及随后的老化过程中发生了结晶。整料的力学性能，如压缩模量和应力，取决于P3HB3HH中3-羟基己酸酯的含量。此外，在植物油-水混合物中，P3HB3HH整料优先吸收亚麻籽油而非水。结合P3HB3HH的生物可降解特性，本研究有望为生物基材料的发展做出贡献。
