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接触多氯联苯(PCBs)的电容器制造工人的短期死亡率和癌症发病率

Short-term mortality and cancer incidence in capacitor manufacturing workers exposed to polychlorinated biphenyls (PCBs).

作者信息

Gustavsson P, Hogstedt C, Rappe C

出版信息

Am J Ind Med. 1986;10(4):341-4. doi: 10.1002/ajim.4700100402.

Abstract

A cohort study of 142 male Swedish capacitor manufacturing workers was performed. PCB had been used as a dielectricum in power capacitors between 1960 and 1978. Mortality was investigated for the period 1965 to 1982 and cancer incidence from 1965 to 1980. Twenty-one deaths and seven cancers were observed, which was in agreement with the anticipated numbers calculated from national statistics. One person had developed two rare tumors, a slow growing mesenchymal tumor (desmoid) and a malignant lymphoma. The results cannot rule out the possibility of a carcinogenic risk from PCB exposure because of the small size of the cohort and relatively brief follow-up period, but they do not indicate any excess mortality or cancer incidence in this factory so far.

摘要

对142名瑞典男性电容器制造工人进行了一项队列研究。1960年至1978年间,多氯联苯曾被用作电力电容器中的电介质。调查了1965年至1982年期间的死亡率以及1965年至1980年期间的癌症发病率。观察到21例死亡和7例癌症,这与根据国家统计数据计算出的预期数字相符。有一人患了两种罕见肿瘤,一种生长缓慢的间叶性肿瘤(硬纤维瘤)和一种恶性淋巴瘤。由于队列规模较小且随访期相对较短,这些结果不能排除多氯联苯暴露致癌风险的可能性,但目前并未表明该工厂存在任何额外的死亡率或癌症发病率。

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