• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Oligosaccharides obtained from a blood-group-Sd(a+) Tamm-Horsfall glycoprotein. An n.m.r. study.从血型为Sd(a+)的Tamm-Horsfall糖蛋白中获得的寡糖。核磁共振研究。
Biochem J. 1986 Jun 15;236(3):821-8. doi: 10.1042/bj2360821.
2
A blood group Sda-active pentasaccharide isolated from Tamm-Horsfall urinary glycoprotein.从Tamm-Horsfall尿糖蛋白中分离出的一种具有Sda血型活性的五糖。
Biochem Biophys Res Commun. 1983 Sep 15;115(2):625-31. doi: 10.1016/s0006-291x(83)80190-9.
3
Oligosaccharides derived by keratanase II digestion of bovine articular cartilage keratan sulphates.通过角质酶II消化牛关节软骨硫酸角质素得到的寡糖。
Eur J Biochem. 1994 Sep 1;224(2):281-308. doi: 10.1111/j.1432-1033.1994.00281.x.
4
Enzyme-aided construction of medium-sized alditols of complete O-linked saccharides. The constructed hexasaccharide alditol Gal beta 1-4GlcNAc beta 1-6Gal beta 1-4GlcNAc beta 1-6(Gal beta 1-3)GalNAc-ol resists the action of endo-beta-galactosidase from Bacteroides fragilis.
FEBS Lett. 1994 Jul 25;349(1):55-9. doi: 10.1016/0014-5793(94)00638-5.
5
The abundance of additional N-acetyllactosamine units in N-linked tetraantennary oligosaccharides of human Tamm-Horsfall glycoprotein is a donor-specific feature.人Tamm-Horsfall糖蛋白N-连接四天线寡糖中额外的N-乙酰乳糖胺单元的丰度是供体特异性特征。
Glycobiology. 1998 Nov;8(11):1065-75. doi: 10.1093/glycob/8.11.1065.
6
Structure determination of oligosaccharides isolated from Cad erythrocyte membranes by permethylation analysis and 500-MHz 1H-NMR spectroscopy.通过全甲基化分析和500兆赫氢核磁共振光谱法对从卡地红细胞膜中分离出的寡糖进行结构测定。
Eur J Biochem. 1985 Jan 2;146(1):125-9. doi: 10.1111/j.1432-1033.1985.tb08628.x.
7
Keratanase digestion of keratan sulphates: characterization of large oligosaccharides from the N-acetyllactosamine repeat sequence and from the non-reducing terminal chain caps.硫酸角质素的角质酶消化：来自N-乙酰乳糖胺重复序列和非还原末端链帽的大寡糖的表征
Biochim Biophys Acta. 1995 May 11;1244(1):17-29. doi: 10.1016/0304-4165(94)00180-6.
8
Immunochemical studies on blood groups. Purification and characterization of radioactive 3H-reduced di- to hexasaccharides produced by alkaline beta-elimination-borohydride 3H reduction of Smith degraded blood group A active glycoproteins.
J Biol Chem. 1984 Jun 10;259(11):7178-86.
9
Single mid-chain GlcNAc beta 1-6Gal beta 1-4R sequences of linear oligosaccharides are resistant to endo-beta-galactosidase of Bacteroides fragilis.
Glycoconj J. 1991 Aug;8(4):376-80. doi: 10.1007/BF00731351.
10
1H-NMR studies at 500 MHz of a neutral disaccharide and sulphated di-, tetra-, hexa- and larger oligosaccharides obtained by endo-beta-galactosidase treatment of keratan sulphate.对通过硫酸角质素的内切-β-半乳糖苷酶处理获得的中性二糖以及硫酸化的二糖、四糖、六糖和更大的寡糖进行500兆赫的1H核磁共振研究。
Eur J Biochem. 1986 Jun 2;157(2):375-84. doi: 10.1111/j.1432-1033.1986.tb09679.x.

引用本文的文献

1
N-Glycans carried by Tamm-Horsfall glycoprotein have a crucial role in the defense against urinary tract diseases.由Tamm-Horsfall糖蛋白携带的N-聚糖在防御泌尿系统疾病中起关键作用。
Glycoconj J. 2005 Nov;22(7-9):383-94. doi: 10.1007/s10719-005-2142-z.
2
Sd(a)-antigen-like structures carried on core 3 are prominent features of glycans from the mucin of normal human descending colon.核心3上携带的Sd(a)抗原样结构是正常人降结肠粘蛋白聚糖的显著特征。
Biochem J. 2001 Sep 15;358(Pt 3):657-64. doi: 10.1042/bj3580657.
3
Conformational analysis of the Sd(a) determinant-containing tetrasaccharide and two mimics in aqueous solution by using 1H NMR ROESY spectroscopy in combination with MD simulations.通过使用¹H NMR ROESY光谱结合分子动力学模拟对含Sd(a)决定簇的四糖及其两种模拟物在水溶液中的构象分析。
J Biomol NMR. 2000 Jan;16(1):59-77. doi: 10.1023/a:1008300916721.
4
Evidence for N-linked glycosylation in Toxoplasma gondii.刚地弓形虫中N-连接糖基化的证据。
Biochem J. 1993 May 1;291 ( Pt 3)(Pt 3):713-21. doi: 10.1042/bj2910713.
5
500 MHz 1H n.m.r. of oligosaccharides of N-acetyl-lactosamine-type released from human erythrocyte glycopeptides by endo-beta-galactosidase.通过内切β-半乳糖苷酶从人红细胞糖肽释放的N-乙酰乳糖胺型寡糖的500兆赫¹H核磁共振谱
Biochem J. 1988 Feb 15;250(1):9-13. doi: 10.1042/bj2500009.
6
Enzymic synthesis, chemical characterisation and Sda activity of GalNAc beta 1-4[NeuAc alpha 2-3]Gal beta 1-4GlcNAc and GalNAc beta 1-4[NeuAc alpha 2-3]Gal beta 1-4Glc.GalNAcβ1-4[NeuAcα2-3]Galβ1-4GlcNAc和GalNAcβ1-4[NeuAcα2-3]Galβ1-4Glc的酶促合成、化学表征及Sda活性
Glycoconj J. 1989;6(3):319-32. doi: 10.1007/BF01047851.
7
Carbohydrate analysis of glycoproteins. A review.糖蛋白的碳水化合物分析。综述。
Appl Biochem Biotechnol. 1990 Jan;23(1):53-80. doi: 10.1007/BF02942052.
8
A non-reducing terminal fragment from tracheal cartilage keratan sulphate chains contains alpha (2-3)-linked N-acetylneuraminic acid.来自气管软骨硫酸角质素链的一个非还原性末端片段含有α(2-3)连接的N-乙酰神经氨酸。
Biochem J. 1991 Sep 15;278 ( Pt 3)(Pt 3):779-85. doi: 10.1042/bj2780779.

本文引用的文献

1
Characterization and separation of an inhibitor of viral hemagglutination present in urine.尿液中存在的病毒血凝抑制物的特性鉴定与分离
Proc Soc Exp Biol Med. 1950 May;74(1):106-8.
2
Detection of sugars on paper chromatograms.纸色谱上糖的检测
Nature. 1950 Sep 9;166(4219):444-5. doi: 10.1038/166444b0.
3
The thiobarbituric acid assay of sialic acids.唾液酸的硫代巴比妥酸测定法。
J Biol Chem. 1959 Aug;234(8):1971-5.
4
Primary-structure determination of fourteen neutral oligosaccharides derived from bronchial-mucus glycoproteins of patients suffering from cystic fibrosis, employing 500-MHz 1H-NMR spectroscopy.利用500兆赫的1H核磁共振光谱法对来自囊性纤维化患者支气管黏液糖蛋白的14种中性寡糖进行一级结构测定。
Eur J Biochem. 1982 Sep;127(1):7-20. doi: 10.1111/j.1432-1033.1982.tb06831.x.
5
N-Acetyl-D-galactosaminyl-beta-(1 goes to 4)-d-galactose: a terminal non-reducing structure in human blood group Sda-active Tamm-Horsfall urinary glycoprotein.N-乙酰-D-半乳糖胺基-β-(1→4)-D-半乳糖：人血型Sda活性的Tamm-Horsfall尿糖蛋白中的一种末端非还原结构。
Biochem Biophys Res Commun. 1982 Jan 15;104(1):58-65. doi: 10.1016/0006-291x(82)91940-4.
6
Structural analysis of the carbohydrate moieties of human Tamm-Horsfall glycoprotein.
Carbohydr Res. 1984 Nov 15;134(1):141-55. doi: 10.1016/0008-6215(84)85029-6.
7
A computerized approach to the analysis of oligosaccharide structure by high-resolution proton n.m.r.一种通过高分辨率质子核磁共振对寡糖结构进行分析的计算机化方法
Biochem J. 1984 Oct 1;223(1):129-43. doi: 10.1042/bj2230129.
8
A blood group Sda-active pentasaccharide isolated from Tamm-Horsfall urinary glycoprotein.从Tamm-Horsfall尿糖蛋白中分离出的一种具有Sda血型活性的五糖。
Biochem Biophys Res Commun. 1983 Sep 15;115(2):625-31. doi: 10.1016/s0006-291x(83)80190-9.
9
Isolation and characterization of an endo-beta-galactosidase from Bacteroides fragilis.脆弱拟杆菌中一种内切β-半乳糖苷酶的分离与鉴定
Biochem J. 1983 Aug 1;213(2):485-94. doi: 10.1042/bj2130485.
10
The human blood-group-Sda determinant: a terminal non-reducing carbohydrate structure in N-linked and mucin-type glycoproteins.
Biochem Soc Trans. 1984 Aug;12(4):596-9. doi: 10.1042/bst0120596.

从血型为Sd(a+)的Tamm-Horsfall糖蛋白中获得的寡糖。核磁共振研究。

Oligosaccharides obtained from a blood-group-Sd(a+) Tamm-Horsfall glycoprotein. An n.m.r. study.

作者信息

Donald A S, Feeney J

出版信息

Biochem J. 1986 Jun 15;236(3):821-8. doi: 10.1042/bj2360821.

DOI:10.1042/bj2360821
PMID:3098239
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1146915/
Abstract

Treatment of Tamm-Horsfall urinary glycoprotein with Bacteroides fragilis endo-beta-galactosidase over a range of enzyme concentrations, pH and temperature resulted in the release of a small but constant proportion of the terminal sugars, which indicates the presence in the glycoprotein of relatively few enzyme-susceptible -GlcNAc beta 1-3Gal beta 1-4GlcNAc- units. Three oligosaccharides were isolated from the enzyme digest and characterized as Gal beta 1-4GlcNAc beta 1-3Gal, NeuAc alpha 2-3Gal beta 1-4 GlcNAc beta 1-3Gal and GalNAc beta 1-4(NeuAc alpha 2-3)Gal beta 1-4GlcNAc beta 1-3Gal by methylation analysis and exo-glycosidase digestion. The alditols of these oligosaccharides and related structures were examined by 500 MHz 1H-n.m.r. spectroscopy aided by spin-spin decoupling and two-dimensional correlated spectroscopy. An almost complete assignment of proton shifts was possible, and significant differences between the signals of some of the protons in the blood-group-Sda-active oligosaccharide III and literature values for the corresponding signals in the structurally related Cad-blood-group determinant are noted.

摘要

在一系列酶浓度、pH值和温度条件下，用脆弱拟杆菌内切β-半乳糖苷酶处理Tamm-Horsfall尿糖蛋白，结果释放出一小部分但比例恒定的末端糖，这表明该糖蛋白中相对较少存在对酶敏感的-GlcNAcβ1-3Galβ1-4GlcNAc-单元。从酶解产物中分离出三种寡糖，并通过甲基化分析和外切糖苷酶消化将其鉴定为Galβ1-4GlcNAcβ1-3Gal、NeuAcα2-3Galβ1-4GlcNAcβ1-3Gal和GalNAcβ1-4(NeuAcα2-3)Galβ1-4GlcNAcβ1-3Gal。借助自旋-自旋去耦和二维相关光谱，通过500MHz 1H-核磁共振光谱对这些寡糖及其相关结构的糖醇进行了研究。几乎可以完全确定质子位移，并且注意到血型-Sda活性寡糖III中某些质子的信号与结构相关的Cad血型决定簇中相应信号的文献值之间存在显著差异。