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慢性失眠的神经生物学机制

Neurobiological Mechanisms In Chronic Insomnia.

作者信息

Perlis Michael, Pigeon Wil, Gehrman Phil, Findley Jim, Drummond Sean

机构信息

Behavioral Sleep Medicine Program, Department of Psychiatry, University of Pennsylvania, Suite 670, 3535 Market Street, Philadelphia, PA 19104.

Sleep and Neurophysiology Research Laboratory, Department of Psychiatry, University of Rochester, 300 Crittenden Boulevard, Rochester, NY 14642.

出版信息

Sleep Med Clin. 2009 Dec;4(4):549-558. doi: 10.1016/j.jsmc.2009.07.002.

DOI:10.1016/j.jsmc.2009.07.002
PMID:30983923
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6457449/
Abstract

This article grapples with the notion that insomnia can or should be defined in physiologic terms. It is proposed that insomnia is better understood from a neurobiological perspective. A review of the neurobiology of sleep and wakefulness is provided with a special emphasis on the implications for insomnia. Following the review it is suggested that a complete understanding of insomnia will require that the neurobiologic characterization of insomnia be informed by modern cognitive concepts and methods.

摘要

本文探讨了失眠可以或应该从生理学角度进行定义这一观点。有人提出，从神经生物学角度能更好地理解失眠。本文对睡眠和觉醒的神经生物学进行了综述，并特别强调了其对失眠的影响。综述之后，有人认为，要全面理解失眠，就需要用现代认知概念和方法来对失眠进行神经生物学特征描述。

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