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经椎间孔腰椎椎体间融合术(TLIF)、后路腰椎椎体间融合术(PLIF)和斜外侧腰椎椎间融合术(XLIF)应用中皮质骨螺钉与椎弓根螺钉固定稳定性的生物力学分析

Biomechanical Analysis of Cortical Versus Pedicle Screw Fixation Stability in TLIF, PLIF, and XLIF Applications.

作者信息

Nomoto Edward K, Fogel Guy R, Rasouli Alexandre, Bundy Justin V, Turner Alexander W

机构信息

Cedars-Sinai Spine Center, Los Angeles, CA, USA.

Spine Pain Be Gone, San Antonio, TX, USA.

出版信息

Global Spine J. 2019 Apr;9(2):162-168. doi: 10.1177/2192568218779991. Epub 2018 Jul 31.

Abstract

STUDY DESIGN

Cadaveric biomechanical study.

OBJECTIVES

Medial-to-lateral trajectory cortical screws are of clinical interest due to the ability to place them through a less disruptive, medialized exposure compared with conventional pedicle screws. In this study, cortical and pedicle screw trajectory stability was investigated in single-level transforaminal lumbar interbody fusion (TLIF), posterior lumbar interbody fusion (PLIF), and extreme lateral interbody fusion (XLIF) constructs.

METHODS

Eight lumbar spinal units were used for each interbody/screw trajectory combination. The following constructs were tested: TLIF + unilateral facetectomy (UF) + bilateral pedicle screws (BPS), TLIF + UF + bilateral cortical screws (BCS), PLIF + medial facetectomy (MF) + BPS, PLIF + bilateral facetectomy (BF) + BPS, PLIF + MF + BCS, PLIF + BF + BCS, XLIF + BPS, XLIF + BCS, and XLIF + bilateral laminotomy + BCS. Range of motion (ROM) in flexion-extension, lateral bending, and axial rotation was assessed using pure moments.

RESULTS

All instrumented constructs were significantly more rigid than intact ( < .05) in all test directions except TLIF + UF + BCS, PLIF + MF + BCS, and PLIF + BF + BCS in axial rotation. In general, XLIF and PLIF + MF constructs were more rigid (lowest ROM) than TLIF + UF and PLIF + BF constructs. In the presence of substantial iatrogenic destabilization (TLIF + UF and PLIF + BF), cortical screw constructs tended to be less rigid (higher ROM) than the same pedicle screw constructs in lateral bending and axial rotation; however, no statistically significant differences were found when comparing pedicle and cortical fixation for the same interbody procedures.

CONCLUSIONS

Both cortical and pedicle trajectory screw fixation provided stability to the 1-level interbody constructs. Constructs with the least iatrogenic destabilization were most rigid. The more destabilized constructs showed less lateral bending and axial rotation rigidity with cortical screws compared with pedicle screws. Further investigation is warranted to understand the clinical implications of differences between constructs.

摘要

研究设计

尸体生物力学研究。

目的

与传统椎弓根螺钉相比,从内侧到外侧轨迹的皮质螺钉因其能够通过干扰性较小的内侧入路置入而具有临床意义。在本研究中,研究了单节段经椎间孔腰椎椎间融合术(TLIF)、后路腰椎椎间融合术(PLIF)和极外侧椎间融合术(XLIF)结构中皮质螺钉和椎弓根螺钉轨迹的稳定性。

方法

每个椎间融合/螺钉轨迹组合使用8个腰椎脊柱单元。测试了以下结构:TLIF+单侧小关节切除术(UF)+双侧椎弓根螺钉(BPS)、TLIF+UF+双侧皮质螺钉(BCS)、PLIF+内侧小关节切除术(MF)+BPS、PLIF+双侧小关节切除术(BF)+BPS、PLIF+MF+BCS、PLIF+BF+BCS、XLIF+BPS、XLIF+BCS以及XLIF+双侧椎板切开术+BCS。使用纯力矩评估屈伸、侧屈和轴向旋转的活动范围(ROM)。

结果

除TLIF+UF+BCS、PLIF+MF+BCS和PLIF+BF+BCS在轴向旋转时外,所有植入器械的结构在所有测试方向上均显著比完整结构更僵硬(P<.05)。总体而言,XLIF和PLIF+MF结构比TLIF+UF和PLIF+BF结构更僵硬(ROM最低)。在存在严重医源性不稳定(TLIF+UF和PLIF+BF)的情况下,皮质螺钉结构在侧屈和轴向旋转时往往比相同的椎弓根螺钉结构更不僵硬(ROM更高);然而,在比较相同椎间融合手术的椎弓根固定和皮质固定时,未发现统计学上的显著差异。

结论

皮质螺钉和椎弓根轨迹螺钉固定均为单节段椎间融合结构提供了稳定性。医源性不稳定最小的结构最僵硬。与椎弓根螺钉相比,不稳定程度更高的结构在使用皮质螺钉时侧屈和轴向旋转刚度较低。有必要进一步研究以了解不同结构之间差异的临床意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dffe/6448199/fc1a4bb8c7b8/10.1177_2192568218779991-fig1.jpg

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