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动力稳定相邻融合与后路腰椎体间融合治疗腰椎退行性疾病的比较:一项荟萃分析。

Dynamic Stabilization Adjacent to Fusion versus Posterior Lumbar Interbody Fusion for the Treatment of Lumbar Degenerative Disease: A Meta-Analysis.

机构信息

Department of Orthopaedics, Xuanwu Hospital Capital Medical University, Beijing 100053, China.

National Clinical Research Center for Geriatric Diseases, Beijing 100053, China.

出版信息

Biomed Res Int. 2020 May 20;2020:9309134. doi: 10.1155/2020/9309134. eCollection 2020.

Abstract

This study evaluated differences in outcome variables between dynamic stabilization adjacent to fusion (DATF) and posterior lumbar interbody fusion (PLIF) for the treatment of lumbar degenerative disease. A systematic review of PubMed, EMBASE, and Cochrane was performed. The variables of interest included clinical adjacent segment pathologies (CASPs), radiological adjacent segment pathologies (RASPs), lumbar lordosis (LL), visual analogue scale (VAS) of back (VAS-B) and leg (VAS-L), Oswestry disability index (ODI), Japanese Orthopaedic Association (JOA) score, duration of surgery (DS), estimated blood loss (EBL), complications, and reoperation rate. Nine articles identified as meeting all of the inclusion criteria. DATF was better than PLIF in proximal RASP, CASP, and ODI during 3 months follow-up, VAS-L. However, no significant difference between DATF and PLIF was found in distal RASP, LL, JOA score, VAS-B, ODI after 3 months follow-up, complication rates, and reoperation rate. These further confirmed that DATF could decrease the proximal ASP both symptomatically and radiographically as compared to fusion group; however, the influence of DATF on functional outcome was similar with PLIF. The differences between hybrid surgery and topping-off technique were located in DS and EBL in comparison with PLIF. Our study confirmed that DATF could decrease the proximal ASP both symptomatically and radiographically as compared to the fusion group; however, the influence of DATF on functional outcome was similar with PLIF. The difference between hybrid surgery and topping-off technique was not significant in treatment outcomes.

摘要

本研究评估了动态稳定相邻融合(DATF)与后路腰椎间融合(PLIF)治疗腰椎退行性疾病的结局变量差异。对 PubMed、EMBASE 和 Cochrane 进行了系统评价。感兴趣的变量包括临床相邻节段病变(CASPs)、放射学相邻节段病变(RASPs)、腰椎前凸(LL)、背部视觉模拟量表(VAS-B)和腿部(VAS-L)、Oswestry 残疾指数(ODI)、日本矫形协会(JOA)评分、手术时间(DS)、估计失血量(EBL)、并发症和再次手术率。确定了 9 篇符合所有纳入标准的文章。在 3 个月随访中,DATF 在近端 RASP、CASP 和 ODI 方面优于 PLIF,VAS-L。然而,在 3 个月随访时,DATF 与 PLIF 在远端 RASP、LL、JOA 评分、VAS-B、ODI 、并发症发生率和再次手术率方面无显著差异。这些进一步证实,与融合组相比,DATF 可以在症状和影像学上降低近端 ASP;然而,DATF 对功能结果的影响与 PLIF 相似。与 PLIF 相比,混合手术和封顶技术在 DS 和 EBL 方面存在差异。我们的研究证实,与融合组相比,DATF 可以在症状和影像学上降低近端 ASP;然而,DATF 对功能结果的影响与 PLIF 相似。混合手术和封顶技术在治疗效果上没有显著差异。

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