Srivastava Dhirendra, Mishra Sonal, Chandra Lokesh, Passi Deepak
Department of Oral and Maxillofacial Surgery, ESIC Dental College and Hospital, Rohini, Delhi, India.
Department of Dentistry, Subdivisional Hospital, Ranchi, Jharkhand, India.
J Family Med Prim Care. 2019 Feb;8(2):748-750. doi: 10.4103/jfmpc.jfmpc_410_18.
Mucormycosis is a rare opportunistic fungal infection with acute, aggressive, and invasive nature, seen in immunocompromised/debilitated patients, especially with diabetes mellitus. The key to successful therapy is the early diagnosis of signs and symptoms of the disease, correction of the underlying medical disorder(s), and aggressive medical and surgical intervention. The case presented here is mucormycotic osteomyelitis of the nasomaxillary-zygomatic complex following trauma in a middle-aged man. Preoperative amphotericin B therapy along with surgical resection of necrotic tissue was done followed by prosthetic rehabilitation with an obturator. There was no sign of recurrence of the diseases for the follow-up period of 1 year.
毛霉病是一种罕见的机会性真菌感染,具有急性、侵袭性和侵入性,多见于免疫功能低下/虚弱的患者,尤其是糖尿病患者。成功治疗的关键在于早期诊断疾病的体征和症状、纠正潜在的内科疾病,以及积极的药物和手术干预。本文介绍的病例是一名中年男性外伤后发生的鼻上颌-颧骨复合体毛霉性骨髓炎。术前采用两性霉素B治疗并手术切除坏死组织,随后用闭孔器进行修复康复治疗。在1年的随访期内,没有疾病复发的迹象。