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化学性髋关节去神经术治疗无法手术的髋部骨折。

Chemical Hip Denervation for Inoperable Hip Fracture.

机构信息

From the Pain Management Unit, Department of Anaesthesia and Intensive Care, Tuen Mun Hospital, Tuen Mun, Hong Kong.

Department of Anaesthesiology, Faculty of Medicine, The University of Hong Kong, Hong Kong.

出版信息

Anesth Analg. 2020 Feb;130(2):498-504. doi: 10.1213/ANE.0000000000004172.

Abstract

BACKGROUND

Hip fracture is a challenging geriatric problem for the health care professionals, especially in patients with multiple comorbidities. In patients with inoperable hip fracture secondary to severe comorbid conditions, the pain can lead to significant challenges in nursing care. With the current understanding of the innervation of hip joint, we are now able to perform selective chemical denervation of the articular branches of femoral and obturator nerves to manage the pain associated with inoperable hip fracture.

METHODS

In this retrospective case series, we analyzed 20 consecutive patients with inoperable hip fracture who received chemical denervation and examined the effect of the denervation on pain and functional outcomes, including the maximally tolerable hip flexion and the ability to sit during their hospital stay. We also assessed the likelihood of being ambulatory as a long-term outcome.

RESULTS

The movement-related pain was significantly reduced at 10 minutes postprocedure, on postintervention days 1 and 5 (P values of <.001), and the degree of maximally tolerable hip flexion was doubled at the same time points (P values of <.001, .003, and .002, respectively). Fifty percent of the patients managed to sit within the first 5 days after procedure, and 3 of them managed to walk with aid 4 months after hip denervation. No procedural adverse event was noted.

CONCLUSIONS

We concluded that this chemical hip denervation could be a safe and effective measure to handle the pain-related and rehabilitation-related challenges as a result of inoperable hip fracture.

摘要

背景

髋部骨折是医疗保健专业人员面临的一项具有挑战性的老年病问题,尤其是对于合并多种合并症的患者。对于因严重合并症而无法手术的髋部骨折患者,疼痛会给护理带来重大挑战。鉴于目前对髋关节神经支配的理解,我们现在能够对股神经和闭孔神经的关节分支进行选择性化学去神经支配,以控制无法手术的髋部骨折相关疼痛。

方法

在这项回顾性病例系列研究中,我们分析了 20 例接受化学去神经支配的无法手术的髋部骨折患者,并检查了去神经支配对疼痛和功能结果的影响,包括最大耐受髋关节屈曲度和住院期间坐立的能力。我们还评估了作为长期结果的可走动的可能性。

结果

手术后 10 分钟,在干预后的第 1 天和第 5 天(P 值均<.001),与运动相关的疼痛明显减轻,同时最大耐受髋关节屈曲度增加了一倍(P 值均<.001,<.003 和<.002)。50%的患者在手术后 5 天内能够坐立,其中 3 名患者在髋部去神经支配后 4 个月能够借助辅助工具行走。未发生任何程序相关的不良事件。

结论

我们得出结论,这种化学性髋关节去神经支配可能是一种安全有效的措施,可以处理因无法手术的髋部骨折而导致的疼痛相关和康复相关的挑战。

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