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用于阻塞性睡眠呼吸暂停低通气综合征的倒刺复位咽成形术(BRP):一项可行性、安全性、有效性及可教授性的初步研究。“我们站在巨人的肩膀上” 。

Barbed reposition pharyngoplasty (BRP) for OSAHS: a feasibility, safety, efficacy and teachability pilot study. "We are on the giant's shoulders".

作者信息

Vicini Claudio, Hendawy Ehsan, Campanini Aldo, Eesa Mohamed, Bahgat Ahmed, AlGhamdi Saleh, Meccariello Giuseppe, DeVito Andrea, Montevecchi Filippo, Mantovani Mario

机构信息

Department of Special Surgery, ENT and Oral Surgery Unit, G.B. Morgagni-L. Pierantoni Hospital, University of Pavia, Forlì, Italy.

出版信息

Eur Arch Otorhinolaryngol. 2015 Oct;272(10):3065-70. doi: 10.1007/s00405-015-3628-3. Epub 2015 Apr 12.

Abstract

A new palatal procedure for snoring/obstructive sleep apnea (OSA) is described. The procedure was named as barbed reposition pharyngoplasty (BRP). The technique is described step by step. The new surgical technique was carried out in ten adult OSA patients with mean age of 53.4 ± 12.4 years (average 30-70) with confirmed retropalatal obstruction. In this pilot study; we assessed the feasibility by calculating the number of cases that failed to be operated and converted to other palatal technique during the same surgical setting, safety was assessed by evaluating both intra-operative and post-operative complications, teachability measured by the learning curve of our team members (the time of surgical procedure). In this study, the technique is proved to be feasible in all cases. There were no significant intra-operative or post-operative complications. Objective clinical improvement was confirmed by polysomnography 6 months post-operative with significant decrease in mean AHI from 43.65 ± 26.83 to 13.57 ± 15.41 (P = 0.007), daytime sleepiness assessed by Epworth Sleepiness Scale from 11.6 ± 4.86 to 4.3 ± 2 (P < 0.01), ODI from 44.7 ± 27.3 to 12.9 ± 16.3 (P = 0.004). Operative time decreased over the course of the study with an initial steep ascent in technical skill acquisition followed by more gradual improvement, and a steady decrease in operative time to as short as 20 min. Our preliminary results suggest that BRP technique is feasible, safe and effective in management of OSA patients. Moreover, it is easy to learn even for not experienced surgeons, less time consuming and with no significant complications.

摘要

本文描述了一种治疗打鼾/阻塞性睡眠呼吸暂停(OSA)的新腭部手术方法。该手术被命名为倒刺复位咽成形术(BRP)。文中逐步介绍了该技术。这项新的外科技术应用于10例成年OSA患者,平均年龄为53.4±12.4岁(年龄范围30 - 70岁),均确诊为腭后阻塞。在这项前瞻性研究中,我们通过计算在同一手术过程中未能进行该手术并转而采用其他腭部技术的病例数来评估可行性,通过评估术中及术后并发症来评估安全性,通过我们团队成员的学习曲线(手术时间)来衡量可传授性。在本研究中,该技术在所有病例中均被证明是可行的。术中及术后均未出现显著并发症。术后6个月通过多导睡眠图证实临床客观改善,平均呼吸暂停低通气指数(AHI)从43.65±26.83显著降至13.57±15.41(P = 0.007),通过爱泼华嗜睡量表评估的日间嗜睡程度从11.6±4.86降至4.3±2(P < 0.01),氧减指数(ODI)从44.7±27.3降至12.9±16.3(P = 0.004)。在研究过程中,手术时间逐渐减少,最初在技术技能掌握阶段上升较陡,随后逐渐改善,手术时间稳步减少至短至20分钟。我们的初步结果表明,BRP技术在OSA患者的治疗中是可行、安全且有效的。此外,即使对于经验不足的外科医生来说也易于学习,耗时较少且无显著并发症。

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