[使用牙膏降低诊室牙齿美白引起的牙齿敏感效果的临床评估]

[Clinical evaluation of the effect of reducing tooth sensitivity caused by in office bleaching using dentifrices].

作者信息

Luo Z Q, Zhang Y, Tang L, Liu Y H

机构信息

Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.

出版信息

Beijing Da Xue Xue Bao Yi Xue Ban. 2019 Apr 18;51(2):340-344. doi: 10.19723/j.issn.1671-167X.2019.02.026.

DOI:10.19723/j.issn.1671-167X.2019.02.026

PMID:30996379

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7441190/

Abstract

OBJECTIVE

To evaluate tooth sensitivity and the efficacy of in-office bleaching when using different desensitizing dentifrices.

METHODS

In total, 150 eligible individuals were recruited and randomized by computer-generated block randomization into three groups: potassium nitrate group (n=50), stannous fluoride group (n=50), and placebo group (n=50). Participants were asked to use a desensitizing dentifrice and toothbrush 15 days prior to and after the in-office bleaching. Each patient received a one-session in-office bleaching with 35% hydrogen peroxide whitening gel. The in-office bleaching included three 15 min operations, totally 45 min. Tooth sensitivity was evaluated by 100 mm visual analog scale (VAS) scores immediately 0 d and 1 d, 2 d, 7 d, 14 d, and 30 d after in-office bleaching. In total, 48 (96%), 45 (90%), and 46 (92%) individuals in the potassium nitrate, stannous fluoride, and placebo groups, respectively, completed the follow-up observations.

RESULTS

Data were analyzed using analysis of covariance (ANOVA). For tooth sensitivity produced by in-office bleaching, the mean VAS values of the three groups were analyzed. At 0 d immediately after surgery, the mean VAS of the potassium nitrate group was 39.22±15.08, which was lower than that of the stannous fluoride group (47.18±12.59) and the placebo group (52.53±14.05), and the difference was statistically significant (P<0.05). The results of the stannous fluoride group and the placebo group were similar, and the difference was not statistically significant (P>0.05). On 1 day postoperatively, the mean VAS of the potassium nitrate group was 38.27±16.52, which was lower than that of the stannous fluoride group (44.69±14.92) and the placebo group (44.45±13.54), P<0.05. The results of the stannous fluoride group and the placebo group were similar, and the difference was not statistically significant (P>0.05). The mean values of VAS were similar 2 d, 7 d, 14 d and 30 d after operation, and the difference was not statistically significant (P>0.05).

CONCLUSION

Compared with the stannous fluoride group and the placebo group, the use of potassium nitrate desensitizing toothpaste 15 days before surgery can effectively alleviate the tooth sensitivity during and after in-office bleaching.

摘要

目的

评估使用不同脱敏牙膏时牙齿敏感性及诊室漂白的效果。

方法

共招募150名符合条件的个体，通过计算机生成的区组随机化将其随机分为三组：硝酸钾组（n = 50）、氟化亚锡组（n = 50）和安慰剂组（n = 50）。参与者在诊室漂白前后15天被要求使用脱敏牙膏和牙刷。每位患者接受一次使用35%过氧化氢美白凝胶的诊室漂白。诊室漂白包括三次15分钟的操作，共45分钟。在诊室漂白后0天、1天、2天、7天、14天和30天立即通过100毫米视觉模拟量表（VAS）评分评估牙齿敏感性。硝酸钾组、氟化亚锡组和安慰剂组分别有48名（96%）、45名（90%）和46名（92%）个体完成了随访观察。

结果

采用协方差分析（ANOVA）对数据进行分析。对于诊室漂白产生的牙齿敏感性，分析了三组的平均VAS值。术后0天，硝酸钾组的平均VAS为39.22±15.08，低于氟化亚锡组（47.18±12.59）和安慰剂组（52.53±14.05），差异有统计学意义（P<0.05）。氟化亚锡组和安慰剂组的结果相似，差异无统计学意义（P>0.05）。术后1天，硝酸钾组的平均VAS为38.27±16.52，低于氟化亚锡组（44.69±14.92）和安慰剂组（44.45±13.54），P<0.05。氟化亚锡组和安慰剂组的结果相似，差异无统计学意义（P>0.05）。术后2天、7天、14天和30天VAS的平均值相似，差异无统计学意义（P>0.05）。