Leroy O, Asseman P, Traisnel G, Durand P, Beuscart R, Dewilde A, Wattré P, Théry C
Arch Mal Coeur Vaiss. 1986 Sep;79(10):1468-73.
During a 4-years period 122 patients admitted to the cardiologic hospital in Lille presented a significative positivity of serological reaction against Coxsackievirus B. Among these patients 19 suffered from acute pericarditis, 4 from cardiac arrhythmias, 3 from Bornholm syndrome and 14 from apparently primary congestive cardiomyopathy. In most of these 14 patients representing 18.4% of congestive cardiomyopathies investigated at the same time, hemodynamic studies and heart scanning with radioactive gallium were performed. 7 of these patients had a chronic (group A) and 7 an acute evolution (group B). In group A the scans were negative 4 times out of 5, whereas in group B they were positive in 5 out of 5 examinations. The control group including 3247 patients coming from the Institut Pasteur exhibited serological positivity in 4.6% of cases. Comparison of this group with that of cardiomyopathies shows a significant difference (p less than 0.001). The authors draw the attention to the frequency of positive serodiagnosis in congestive cardiomyopathy and stress the importance of gallium scintiscanning.
在4年期间，里尔心脏病医院收治的122例患者血清学反应对柯萨奇病毒B呈显著阳性。在这些患者中，19例患有急性心包炎，4例患有心律失常，3例患有博恩霍尔姆综合征，14例患有明显的原发性充血性心肌病。在这14例患者中，占同期所研究充血性心肌病的18.4%，大多数患者进行了血液动力学研究和放射性镓心脏扫描。其中7例患者为慢性病程（A组），7例为急性病程（B组）。A组扫描结果5次中有4次为阴性，而B组5次检查中有5次为阳性。包括来自巴斯德研究所的3247例患者的对照组血清学阳性率为4.6%。该组与心肌病组比较有显著差异（p<0.001）。作者提请注意充血性心肌病血清学诊断阳性的频率，并强调镓闪烁扫描的重要性。
