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一名青少年的灾难性小脑炎:病例报告

Catastrophic Cerebellitis in an adolescent: A Case Report.

作者信息

Kashikar Shivali V, Lakhkar Bhushan, Pandey Ankur, Gupta Aanchal

机构信息

Radiology Associate Professor, Jawaharlal Nehru Medical College, Sawangi Meghe, Wardha 442001, Maharashtra, India.

Professor, Radiology, Jawaharlal Nehru Medical College, Sawangi Meghe, Wardha 442005, Maharashtra, India.

出版信息

Oman Med J. 2014 Jul;29(4):e075. doi: 10.5001/omj.2014.84.

Abstract

An adolescent presented with headache and projectile vomiting and showed ataxia, dysarthia and nystagmus with normal cognition. A diagnosis of acute cerebellitis was made on the basis of computed tomography and magnetic resonance imaging findings. He developed seizures and had a rapid downhill course with death at 48 hours after admission. Clinically, patients of acute cerebellitis present with fever, nausea, headache and altered sensorium with cerebellar symptoms. Inflammation of the cerebellum compresses the brain stem and induces mental alterations. It is a rare pathology developing due to an infectitious cause, post-infectitious or post vaccination etiology. Many times it is not possible to identify the causative agent. Cerebellitis can be mild where recovery occurs in few weeks and no abnormalities are seen on diagnostic imaging studies. On the other end, severe cases have focal neurological deficits, altered consciousness, raised intracranial pressure and abnormal neuroimaging. Treatment should be tailored to individual needs according to presentation, severity, and etiology. We discuss clinical features, diagnosis and management of acute cerebellitis which is an important cause of acute cerebellar functional disorder in childhood.

摘要

一名青少年出现头痛和喷射性呕吐,伴有共济失调、构音障碍和眼球震颤,但认知正常。根据计算机断层扫描和磁共振成像结果诊断为急性小脑炎。他出现了癫痫发作,病情迅速恶化,入院48小时后死亡。临床上,急性小脑炎患者表现为发热、恶心、头痛和意识改变,并伴有小脑症状。小脑炎症会压迫脑干并导致精神改变。这是一种由感染性病因、感染后或疫苗接种后病因引起的罕见病理情况。很多时候无法确定病原体。小脑炎可能较轻,数周内即可恢复,诊断性影像学检查未见异常。另一方面,严重病例有局灶性神经功能缺损、意识改变、颅内压升高和神经影像学异常。应根据临床表现、严重程度和病因制定个体化治疗方案。我们讨论了急性小脑炎的临床特征、诊断和管理,急性小脑炎是儿童急性小脑功能障碍的重要原因。

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